摘要
目的分析1990年和2010年中国人群感染性腹泻的疾病负担及其变化。方法利用2010年全球疾病负担研究结果,以2010年全国人口普查数据作为标准人口计算标化率,分性别和年龄对感染性腹泻的发病、死亡和疾病负担情况进行对比分析。主要指标包括发病数和发病率、死亡数和死亡率、早死造成的生命损失年（YLL）、伤残造成的生命损失年（YLD）和伤残调整寿命年（DALY）。结果 2010年中国人群感染性腹泻发病886 000 955.60例,标化发病率71 009.26/10万,死亡4364.14例,标化死亡率0.37/10万,造成的YLL、YLD和DALY分别为226 660.71人年、1 070 780.40人年和1 297 441.10人年,YLL率、YLD率和DALY率分别为24.66/10万、97.96/10万和122.62/10万。与1990年相比,2010年发病指标有所下降,发病数和标化发病率分别下降6.94%和14.24%,死亡指标大幅下降,死亡数和标化死亡率分别下降93.88%和93.86%,YLL、标化YLL率、YLD、标化YLD率、DALY和标化DALY率降幅分别为95.17%、93.90%、18.81%、14.43%、78.43%和76.35%。中国感染性腹泻的疾病负担主要集中在5岁以下儿童。轮状病毒性肠炎是我国〈5岁组儿童感染性腹泻的主要疾病负担,产毒性大肠埃希菌感染是5~69岁组和70岁及以上人群的主要疾病负担。结论与1990年相比,2010年我国人群感染性腹泻疾病负担大幅降低。5岁以下儿童是我国感染性腹泻防控的重点人群。
Objective To understand the disease burden of diarrhea in China in 1990 and 2010 and compare the difference between the two years. Methods The data of the Global Burden of Disease Study 2010（ GBD 2010） were used,the burden of diarrhea for Chinese population in 1990 and 2010 were analyzed and gender and age specific morbidity,mortality,years of life lost due to premature mortality（ YLL）,years lived with disability（ YLD）,disability adjusted life years（ DALY） were calculated by using data of 2010 national census as standard. Results In 2010,a total of 886 000 955. 60 cases of diarrhea,including 4364. 14 deaths were reported in China,the standardized morbidity and the standardized mortality were 71 009. 26 /lakh and 0. 37 / lakh, respectively and the related DALY, standardized DALY, YLL, standardized YLL, YLD, and standardized YLD were 226 660. 71 person years（ PYRS）,24. 66 PYRS / lakh,1 070 780. 40 PYRS,97. 96 PYRS / lakh,1 297 441. 10 PYRS,and 122. 62 PYRS / lakh,respectively. Compared with 1990,the above mentioned indicator values decreased by 6. 94%,14. 24%,95. 17%,93. 90%,18. 81%,14. 43%,78. 43% and 76. 35%,respectively,in 2010. The burden of diarrheal diseases was heavy in children aged 〈 5 years, and Rotavirus enteritis was the major disease,Enterotoxigenic E. coli infection was the major disease in people both aged 5- 69 years and aged ≥70 years. Conclusion Compared with 1990,all the values of indicators showing the burden of diarrheal diseases in Chinese declined significantly in2010. Children aged 5 years was the key population in diarrheal disease prevention and control.
出处
《疾病监测》
CAS
2016年第3期233-239,共7页
Disease Surveillance
基金
国家科技支撑计划(No.2013BAI04B02)
中国疾病预防控制中心青年科研基金项目(No.2015A204)~~
关键词
疾病负担
早死造成的生命损失年
伤残造成的生命损失年
伤残调整生命年
感染性腹泻
Burden of diarrheal diseases
Incidence
Years of life lost due to premature mortality
Years lived with disability
Disability adjusted life years
作者简介
王琦琦，女，四川省绵竹市人，助理研究员，硕士研究生，主要从事流行病学方法在公共卫生实践中的应用研究
通信作者：孙谨芳，Tel：010-58900524，Email：sunjf@chinacdc．cn
