摘要
目的探讨高校教师脂肪肝与颈动脉内中膜层厚度(intima-media thickness,IMT)及颈动脉血管斑块的关系。方法选择2010年1月至2014年12月在某校医院门诊行腹部超声检查的脂肪肝患者97例为脂肪肝组,选择同期门诊行腹部超声检查排除脂肪肝的103例作为非脂肪肝组,超声检测两组患者的颈动脉IMT和斑块发生情况,同时测量身高、体重,计算体质指数(BMI),空腹检查血糖(FPG)、血脂等,并对资料进行统计学分析。结果脂肪肝组BMI、甘油三酯(TG)、总胆固醇(TC)、FPG、糖化血红蛋白(HbAlc)、颈动脉IMT和粥样斑块检出率均显著高于非脂肪肝组,差异有统计学意义(P=0.000);脂肪肝组HDL显著低于非脂肪肝组(t=-2.688,P=0.008);两组LDL、UA比较,差异无统计学意义(t=1.755,1.301;P=0.081,0.195)。结论脂肪肝与颈动脉IMT、颈动脉粥样硬化密切相关。对于腹部超声检查发现脂肪肝的患者应同时行颈动脉超声检查,及早进行临床干预以减少心脑血管事件的发生。
Objective To explore the relationship between fatty liver and carotid artery intimal-media thickness （IMT） and plaque in college teachers. Methods Total of 97 patients who were diagnosed with fatty liver disease through abdominal ultrasound from January 2010 to December 2014 were selected as fatty liver group, and 103 cases without fatty liver disease were selected as non fatty liver group. The carotid IMT and plaque were examined by ultrasound. The height, body weight, BMI, plasma levels of FPG and blood lipid of the patients were detected and analyzed. Results In fatty liver group, BMI, total cholesterol （TG）, total cholesterol （TC）, fasting blood glucose （FPG）, glycosylated hemoglobin （HbAlc）, carotid IMT and atherosclerotic plaque were significantly higher than those in non fatty liver group. The difference between the two groups was statistically significant （P = 0.000）. The level of HDL in non fatty liver group was significantly lower than that in fatty liver group （t = -2.688, P = 0.008）, while no significant differences were observed in plasma LDL and UA between the two groups（t = 1.755, 1.301; P = 0.081, 0.195）. Conclusions Fatty liver disease is closely associated with intimal-medial thickness and carotid atherosclerosis. Patients diagnosed with fatty liver by abdominal ultrasound should also be performed with carotid artery ultrasound examination to conduct early clinical intervention and reduce the occurrence of cardiovascular and cerebrovascular events.
出处
《中国肝脏病杂志（电子版）》
CAS
2016年第1期100-102,共3页
Chinese Journal of Liver Diseases：Electronic Version
基金
2015年华北电力大学中央高校基本科研专项资金项目(2015QN26)
关键词
脂肪肝
动脉粥样硬化
超声检查
Fatty liver disease
Atherosclerosis
Ultrasonography
作者简介
通讯作者：陈红艳Email：chenhongyan75@sina．cn
