摘要
用微乳化技术结合复合团聚法制备了纳米及亚微米茄红素胶囊,基于动态光散射测量分析了环境p H值对胶囊的粒径大小及其分布的影响.结果表明,对纳米茄红素胶囊,当p H值为3.5、6.0及6.8时能稳定的分散,而p H值为7.4时则会出现明显的聚集现象;对亚微米茄红素胶囊,当p H值为3.5、6.0、6.8及7.4时其粒径分布均为双峰状态,其中粒径较大的为亚微米茄红素胶囊,粒径较小的为包覆不良的颗粒,且p H=7.4时的粒径明显小于其它三种p H值时的粒径.虽然亚微米胶囊在p H=7.4时粒径明显变小的结果与纳米胶囊相同,但亚微米胶囊并不像纳米胶囊那样出现聚集现象.
Nano and submicron lycopene capsules are prepared by micro- emulsion technology combined with composite reunion method and the effect of pH value on the particle size and its distribution are measured by dy- namic light scattering in this study. The results show that, lycopene nanocapsules can disperse stably at pH = 3.5, 6.0 and 6. 8. There is obvious aggregation at pH = 7.4. The particle size distributions of submicron cap- sules present bimodal state at pH = 3.5, 6. 0, 6. 8 and 7.4 and the size at pH = 7.4 is significantly greater than that of other three pH values. The sizes of submicron capsules and nanocapsules become smaller, but the aggre- gation appeared for nano capsules is not produced for submicron capsules at pH = 7.4
出处
《原子与分子物理学报》
CAS
CSCD
北大核心
2016年第2期240-244,共5页
Journal of Atomic and Molecular Physics
基金
国家自然科学基金(41105107)
陕西省自然科学基础研究计划基金(2012JM5014)
陕西省教育厅科学研究计划基金(2013JK0617)
关键词
动态光散射
粒径测量
茄红素胶囊
PH值
稳定性
Dynamic light scattering
Particle sizing
Lycopene capsules
pH value
Stability
作者简介
孙彦清（1959-），男，教授，主要研究领域为量子统计物理、光散射技术应用．E-mail：yqsun_hz@163.com
