摘要
目的:研究头颈部肿瘤放疗后患者的中医证候特点。方法:采用回顾性分析对67例头颈部肿瘤放疗后患者的临床资料进行整理,频数分析归纳主要的症状及舌象、脉象,进行聚类分析,对聚类结果进行中医辨证,研究各证型特点、KPS评分等相关因素,分析其证候演变及预后情况。结果:1头颈部肿瘤放疗后患者证型为肝郁脾虚证、气阴两虚证、痰湿凝聚证和热毒瘀结证。2热毒瘀结证患者的KPS评分最低、体力差。3痰湿凝聚证和热毒瘀结证患者死亡率高于肝郁脾虚证和气阴两虚证。结论:头颈部肿瘤放疗后多伤及肝脾,出现气虚、阴虚等虚证表现,病变日久,可逐渐出现虚实夹杂,演变为血瘀、痰凝等证型。
Objective：To discuss TCM syndromes characteristics of head and neck cancer after radiotherapy. Methods：Using the methods of retrospective survey 67 cases of patients with head and neck cancer after radiotherapy,summarizing the clinical data and taking frequency analysis of the main symptoms,tongue and pulse condition. Making clustering analysis,analyzing the clustering result,studying the factors related to syndrome characteristics,KPS score,analyzed its syndrome evolution and prognosis. Results：①The head and neck neoplasm patients who have taken the irradiation remedy are syndrome differentiations as liver stagnation and spleen deficiency type,Qi and Yin insufficiency type,sputum and wet condensation,heat toxin blood stagnancy type,in total of four syndromes.②The head and neck neoplasm patients who have taken the irradiation remedy with heat toxin blood stagnancy type have lower scores of KPS,and worst physical power.③The mortality of sputum and wet condensation and heat toxin blood stagnancy type is higher than liver stagnation and spleen deficiency type and Qi and Yin insufficiency type. Conclusion：Head and neck cancer after radiotherapy more easily injuries liver and spleen,appearing Qi deficiency,yin deficiency performance. With the passing of time,the mixture of deficiency syndrome and sthenia pathogenic factors appears little by little. Evolving into blood stasis and tanning type,etc.
出处
《辽宁中医药大学学报》
CAS
2016年第4期185-188,共4页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
头颈部恶性肿瘤
聚类分析
中医辨证
head and neck cancer
cluster analysis
TCM syndrome differentiation
作者简介
尹申（1989-），女，四川筠连人，医师，硕士，研究方向：肿瘤内科学。
通讯作者：殷东风（1958-），男，辽宁沈阳人，教授、主任医师，博士研究生导师，研究方向：恶性肿瘤的中西医结合治疗。E-mail：lnzy_oncology@aliyun．com。
