期刊文献+

T2mapping序列在早期强直性脊柱炎骶髂关节病变中的应用价值 被引量:10

The application value of T2-mapping sequence in the sacroiliac joint lesions of early ankylosing spondylitis
在线阅读 下载PDF
导出
摘要 目的通过测量骶髂关节面下骨髓T2值,探讨T2mapping对强直性脊柱炎早期骶髂关节病变的诊断价值。方法收集我院36例初步诊断为强直性脊柱炎的患者为病例组,24例健康体检者为对照组,分别测量病例组骶髂关节面下病变区及周围相对正常区、对照组骶髂关节面下骨髓的T2值,采用两独立样本t检验对两组骶髂关节面下骨髓的T2值进行统计分析,并采用配对t检验对病例组病变区及周围相对正常区骨髓的T2值进行分析。结果与对照组相比,病例组骶髂关节面下骨髓T2值明显升高,差异有统计学意义(P<0.01)。病例组中病变区比周围相对正常区骨髓T2值升高,差异有统计学意义(P<0.01)。结论 T2mapping序列通过测量骨髓T2值的变化,可以更早的发现强直性脊柱炎患者早期骶髂关节的病变。 Objective To determine the value of T2 mapping of ankylosing spondylitis in the early diagnostic value of sacroiliac joint lesions.Me thods 36 patients with ankylosing spondylitis by cases and 24 healthy controls were collected.The case group were measured sacroiliac joint lesions area and the surrounding relatively normal area,the control group were measured under the sacroiliac joint surface T2 values in the bone marrow,and statistical analysis.Re sults Compared with the control group,the cases of sacroiliac joint surface bone marrowT2 value increased significantly,the difference was statistically significant( P〈0.01).The mean of T2 value in the lesion area higher than the surrounding relatively normal area,the difference was statistically significant( P〈0.01).Conclusion By measuring the changes of the bone marrowT2 values,T2 mapping sequences could detect early sacroiliac joint lesions of ankylosing spondylitis patients.
出处 《中国骨质疏松杂志》 CAS CSCD 北大核心 2016年第3期348-350,357,共4页 Chinese Journal of Osteoporosis
关键词 强直性脊柱炎 骶髂关节 T2mapping 骨髓 Ankylosing spondylitis Sacroiliac joint T2mapping Bone marrow
作者简介 通讯作者:李白艳,Email:BYL318@163.com
  • 相关文献

参考文献14

  • 1吴珊珊,段振华,潘发明.强直性脊柱炎流行病学研究进展[J].安徽医科大学学报,2013,48(8):988-992. 被引量:152
  • 2Cauii A. Increased level of HLA-B27 expression in ankylosingspondylitis patients compared with healthy HLA -B27 -positivesubjects : a possible further susceptibility factor for thedevelopment of disease. Rheumatology ( Oxford ),2002. 41(12): 1375-9.
  • 3杨泽宏,蒋伟,陈建宇,蔡兆熙,刘珍珍,钟镜联,叶瑞心,白志强,梁碧玲.正常人骶髂关节骨髓T_2值初步探讨[J].影像诊断与介入放射学,2013,22(5):361-363. 被引量:11
  • 4甄涛,胡大成,陈文辉.T2mapping序列对强直性脊柱炎的早期诊断价值[J].浙江临床医学,2015,17(3):344-345. 被引量:5
  • 5Rudwaleit, M., The development of Assessment ofSpondyloarthritis international Society classification criteria foraxial spondyloarthritis ( part I) : classification of paper patients byexpert opinion including uncertainty appraisal. Ann Rheum Dis,2009. 68(6); p. 770-776.
  • 6Rudwaleit M, van der Heijde D, Landew6 R, et al. Thedevelopment of Assessment of Spondyloarthritis internationalSociety classification criteria for axial spondyloarthritis ( part II):validation and final selection. Ann Rheum Dis,2009,68 : 777-783.
  • 7张秀梅,崔亚洲,韩金祥.强直性脊柱炎致病机制研究进展[J].国际骨科学杂志,2011,32(3):170-172. 被引量:9
  • 8徐启兰,洪国斌,刘强,王一兵,吴文浩,李文娟,阳莹丽.T2*-mapping用于青年志愿者骶髂关节软骨成像的初步研究[J].医学影像学杂志,2015,25(7):1269-1272. 被引量:4
  • 9LiebI H,Joseph G, Nevitt MC , et al. Early T2 changes predictonset of radiographic knee osteoarthritis : data from theosteoarthritis initiative [ J ]. Ann Rheum Dis, 2015 , 74 : 1353-1359.
  • 10Filardo G, Vannini F, Marcacci M, et al. Matrix-assistedautologous chondrocyte transplantation for cartilage regenerationin osteoarthritic knees : results and failures at midterm follow- up[J]. Am J Sports Med, 2013,41(1): 95-100.

二级参考文献63

  • 1邓世华,刘源.MRI诊断强直性脊柱炎中轴骨关节病变的展望[J].影像诊断与介入放射学,2007,16(3):141-144. 被引量:5
  • 2Hukuda S, Minami M, Saito T, et al. Spondyloarthropathies in Ja- pan : nationwide questionnaire survey performed by the Japan Anky- losing Spondylitis Society[ J]. J Rheumatol,2001,28 ( 3 ) :554 - 9.
  • 3Carbone L D, Cooper C, Michet C J, et al. Ankylosing spondylitis in Rochester,Minnesota, 1935 - 1989. Is the epidemiology chan- ging[ J]. Arthritis Rheum, 1992,35 ( 12 ) : 1476 - 82.
  • 4Kaipiainen-Seppanen O, Aho K, Heliovaara M. Incidence and prev- alence of ankylosing spondylitis in Finland [ J ]. J Rheumatol, 1997,24(3) :496 -9.
  • 5Bakland G, Nossent H C, Gran J T. Incidence and prevalence of ankylosing spondylitis in northern norway [ J ]. Arthritis Rheum, 2005,53 (6) :850 -5.
  • 6Feldtkeller E, Khan M A, van der Heijde D. Age at disease onset and delayed diagnosis of spondyloarthropathies [ J ]. Z Rheumatol, 1999,58(1) :21 -30.
  • 7Brown M A, Laval S H, Brophy S, et al. Recurrence risk modelling of the genetic susceptibility to ankylosing spondylitis [ J ]. Ann Rheum Dis,2000,59( 11 ) :883 -6.
  • 8Burton P R, Clayton D G, Cardon L R,et al. Association scan of 14 500 nonsynonymous SNPs in four diseases identifies autoimmu- nity variants [ J ]. Nat Genet ,2007,39 ( 11 ) : 1329 - 37.
  • 9Wang X, Huang J, Lin Z, et al. Single-nucleotide polymorphisms and expression of IL23R in Chinese ankylosing spondylitis patients [ J]. Rheumatol Int,2010,30(7) : 955 - 9.
  • 10Rueda B,Orozco G,Raya E,et al. The IL23R Arg381Gln non-syn- onymous polymorphism confers susceptibility to ankylosing spondy- litis [ J]. Ann Rheum Dis ,2008,67 (10) : 1451 - 4.

共引文献171

同被引文献75

引证文献10

二级引证文献83

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部