右美托咪啶对淋巴水肿胸导管探查术患者全麻效应的影响被引量：5

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摘要目的:探讨右美托咪啶对胸导管探查术患者全麻效应的影响。方法:住院患者40例,随机均分两组:一组为D组(右美托咪啶组,负荷量为0.8μg/kg,15 min内,维持量0.4μg/(kg·h);另一组为N组(生理盐水对照组)。比较两组患者麻醉用药,苏醒期质量,苏醒时间,不同时点心率、平均动脉压变化及围术期不良事件发生情况。结果:(1)D组患者术中丙泊酚、瑞芬用量及苏醒期躁动评分均明显低于N组,差异有统计学意义(P<0.05);睁眼时间、拔管时间及镇静评分,两组无统计学差异(P>0.05)。(2)两组患者平均动脉压比较:入室后(T1)、手术结束时(T4)及离室时(T6)两组间均无统计学差异(P>0.05),气管插管时(T2)、切皮时(T3)及拔管时(T5),D组均低于N组,均有统计学差异(P<0.01);心率比较:入室后(T1)及手术结束时(T4)两组间均无统计学差异(P>0.05),气管插管时(T2)、切皮时(T3)、拔管时(T5)及离室时(T6),D组心率均低于N组,有显著统计学差异(P<0.05)。(3)术后D组不良事件发生少于N组。结论 :右美托咪啶负荷剂量0.8μg/kg,维持量0.4μg/kg,能够预防淋巴外科手术中气管插管反应,提高苏醒质量;但在拔管后仍需临床常规监护,防治心动过缓等不良事件的发生,保证患者安全。

作者冯枫唐祎航关雷

机构地区首都医科大学附属北京世纪坛医院麻醉科中国航天科工集团七三一医院麻醉科

出处《实用医学杂志》 CAS 北大核心 2016年第5期815-818,共4页 The Journal of Practical Medicine

关键词淋巴水肿右美托咪啶苏醒质量全身麻醉

分类号 R614.2 [医药卫生—麻醉学]

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