摘要
目的通过分析心脑血管药物不良反应,探讨治疗心脑血管疾病的合理用药对策。方法选取2012~2014年我院心脑血管疾病用药发生不良反应的200例患者为研究对象,运用数据挖掘方法,分析不良反应的类别与药物品种之间的关联,探讨不良反应发生的原因,提出优化心脑血管用药的对策。结果肝功能异常、肾功能损伤和呼吸系统异常是心脑血管药物常见的不良反应,多种药物合用更容易引发不良反应。药物本身缺乏靶向性和医生选用不合适的药物治疗是主要的诱因。结论心脑血管药物引发不良反应比较普遍,肝肾功能损伤和呼吸系统异常最常见;引发不良反应的主要原因是药物治疗缺乏靶向性,合理用药、用药个体化和增加药物治疗的靶向性是解决问题的关键。
Objective To analyze the cardiovascular adverse drug reactions in order to explore countermeasures for rational use of drugs. Methods 200 cases of cardiovascular adverse drug reactions between 2012 and 2014 were chosen as research objects. Data mining algorithm was used to analyze the categories of adverse reactions and the correlation between the reactions and drug varieties.The adverse reactions causes were investigated, and the countermeasures of optimizing cardiovascular medication were put forward.Results The common adverse reactions to cardiovascular drugs included liver dysfunction, renal function damage, and respiratory abnormalities. The mixed usage of drugs could more easily cause adverse reactions. The main reasons were the lack of drug targeting and the improper selection of drugs by doctors. Conclusion Cardiovascular drugs can cause adverse reactions in which liver and renal function damage and respiratory abnormalities are the most common. The main reason is the lack of drug targeting. Rational use of drugs, individualized drug use, and increasing drug targeting are countermeasures to solve the problem.
出处
《西南国防医药》
CAS
2016年第3期290-292,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
心脑血管
药物
不良反应
合理用药
cardiovascular
drug
adverse reaction
rational drug use
