摘要
目的：比较腹腔镜与开腹结直肠癌切除术后远期生存率和并发症发生率的差异。方法：检索1998年1月至2015年7月公开发表关于腹腔镜与传统开腹结直肠癌切除术的随机对照研究（RCT）,提取数据进行分析。结果：共21篇RCT（7 501例结直肠癌患者）纳入本研究。腹腔镜术后总生存率[HR=0.85;95%CI（0.75-0.95）]比开腹高;无病生存率[HR=0.93;95%CI（0.82-1.03）]和开腹差异无统计学意义;部分并发症发生率低于开腹手术。结论：腹腔镜结直肠癌切除术后远期总生存率优于开腹手术。
Objective To compare the complication rate and long-term outcomes of laparoscopic surgery and conventional open surgery for colorectal cancer. Methods Published randomized controlled trial（RCT） reports（1998.1-2015.7） of laparoscopic surgery and open surgery for colorectal cancer were searched, and the complication rate and long-term factors were extracted to perform meta-analysis. Results A total of 21 RCT reports involving 7 501 colorectal cancer patients were included in this study. Overall survival（HR = 0.85; 95%CI 0.75 to0.95） of laparoscopic surgery was higher than that of open surgery. There was no statistically significant difference in disease-free survival（HR = 0.93; 95%CI 0.82 to1.03） but the rates of some complications of laparoscopic surgery were lower than those of open surgery. Conclusions Long-term overall survival of laparoscopic colorectal cancer resection is higher than that of open surgery.
出处
《实用医学杂志》
CAS
北大核心
2016年第2期291-294,共4页
The Journal of Practical Medicine
关键词
结直肠癌
腹腔镜
并发症
总生存率
META分析
Colorectal cancer
Laparoscopic
Complication
Overall survival
Meta analysis
作者简介
通信作者：徐亮E—mail：932281936@qq．com
