经皮冠状动脉介入术治疗不稳定型心绞痛患者左心室收缩功能及同步性变化被引量：7

在线阅读下载PDF

导出

摘要目的观察经皮冠状动脉介入术(PCI)治疗不稳定型心绞痛(UA)患者的左心室收缩功能及同步性变化。方法左前降支梗阻的UA患者35例(观察组),采用PCI治疗;另选同期健康体检者25例作为对照(对照组)。两组均进行实时三维超声心动图检查,比较两组左心室整体功能参数、节段功能参数及同步性参数。结果与对照组比较,观察组术前整体收缩末期容积(g ESV)、R-R间期校正的左心室16节段达到最小容积时间的标准差(Tmsv16-SD%)增加,整体射血分数(g EF)、峰值射血率(PER)/左心室整体舒张末期容积(g EDV)减小;与术前比较,观察组术后g ESV、Tmsv16-SD%减小,g EF、PER/g EDV增加。与对照组比较,观察组术前前壁心尖段节段舒张末期容积(r EDV)增加;与对照组比较,观察组术后前壁心尖段r EDV减小。与对照组比较,观察组术前左前降支供血节段(除前间隔基底段外)的节段收缩末期容积(r ESV)增加;与术前比较,观察组术后左前降支供血节段(除前间隔基底段外)r ESV减小。与对照组比较,观察组术前左前降支供血节段(除前间隔基底段外)节段射血分数(r EF)减小;与术前比较,观察组术后左前降支供血节段(除前间隔基底段外)r EF增加。P均<0.05。结论 UA患者PCI术前左心室收缩功能及同步性均降低,术后左心室整体收缩功能及节段收缩功能增强,左心室收缩同步性得到改善。

作者白雪陈东风王少春

机构地区天津医科大学研究生院济宁医学院附属医院山东省心脏疾病诊疗重点实验室

出处《山东医药》 CAS 北大核心 2016年第3期49-51,共3页 Shandong Medical Journal

关键词实时三维超声经皮冠状动脉介入术不稳定型心绞痛左心室功能

分类号 R445.1 [医药卫生—影像医学与核医学]

作者简介陈东风（E-mail：jyfycdf@aliyun．com）

引文网络
相关文献

参考文献25

1Gibson CM.Has my patient achieved adequate myocardial reperfusion[J].Circulation,2003,108(5):504-507.
2Caiani EG,Corsi C,Zamorano J,et al.Improved semiautomated quantification of left ventricular volumes and ejection fraction using3-dimensional echocardiography with a full matrix-array transducer:comparison with magnetic resonance imaging[J].J Am Soc Echocardiography,2005,18(8):779-788.
3Zhang Q,Yu CM,Fung J,et al.Assessment of the effect of cardiac resynchronization therapy on intraventricular mechanical synchronicity by regional volumetric changes[J].Am J Cardiol,2005,95(1):126-129.
4Schindera ST,Mehwald PS,Sahn DJ,et al.Accuracy of real-time three-dimensional echocardiography for quantifying right ventricular volume:static and pulsatile flow studies in an anatomic in vitro model[J].Ultrasound Med,2002,21(10):1069-1075.
5Yusuf S,Mehta SR,Zhao F,et al.Early and late effects of clopidogrel in patients with acute coronary syndromes[J].Circulation,2003,107(7):966-972.
6杨焕宇,刘芳草,曹晓玉,于淼.PCI术在冠心病治疗中的功过[J].首都食品与医药,2015,0(5):60-60. 被引量：3
7Ziad Z,Raimund E,Joerg B,et al.Analysis of global systolic and diastolic left ventricular performance using volume-time curves by real-time three-dimensional echocardiography[J].J Am Soc Echocardiogr,2003,16(1):29-37.
8Caiani EG,Corsi C,Zamorano J,et al.Improved semiautomated quantification of left ventricular volumes and ejection fraction using3-dimensional echocardiography with a full matrix-array transducer:comparison with magnetic resonance imaging[J].J Am Soc Echocardiography,2005,18(8):779-788.
9Chukwu EO,Barasch E,Mihalatos DG,et al.Relative importance of errors in left ventricular quantitation by two-dimensional echocardiography:insights from three-dimensional echocardiography and cardiac magnetic resonance imaging[J].J Am Soc Echocardiogr,2008,21(9):990-997.
10Sugeng L,Mor-avi V,Weinert L,et al.Quantitative assessment of left ventricular size and function:side-by-side comparison of realtime three-dimensional echocardiography and computed tomography with magnetic resonance reference[J].Circulation,2006,114(7):654-666.

二级参考文献30

1张峰,张涛,朱肖星,刘琳娜,李晨,梅其炳.一氧化氮供体对过氧化氢引起的心肌细胞损伤的保护作用[J].生理学报,2004,56(4):481-486. 被引量：9
2冯晓东,张顺业,王海曙,张勇,王学斌,姚滨,王建忠.非体外循环不停跳冠状动脉旁路移植术220例分析[J].中国药物与临床,2006,6(2):140-141. 被引量：2
3Sinha MK,Roy D,Gaze DC,et al.Role of "Ischemia modified albumin",a new biochemical marker of myocardial ischaemia,in the early diagnosis of acute cornary syndromes[J].Emerg Med J,2004;21(1):29-34.
4Anwaruddin S,Januzzi JL Jr,Baggish AL,et al.Ischemia-modified albumin improves the usefulness of standard cardiac biomarkers for the diagnosis of myocardial ischemia in the emergency department setting[J].Am J Clim Pathol,2005;123(1):140-5.
5Perkins ND.Integrating cell-signalling pathways with NF-kappaB and IKK function[J].Nat Rev Mol Cel Biol,2007;8(1):49-62.
6Ito T,Ikeda U.Inflammatory cytokines and cardiovascular disease[J].Curr Drug Targets inflamm Allergy,2003;2(3):257-65.
7Valen G,Paulsson G,Vaage J.Induction of inflammatory mediators during reperfusion of the human heart[J].Ann Thorac Surg,2001;71(1):226-32.
8Monaco C,Paleolog E.Nuclear factor-kappa B:a potential therapeutic target in athemsclemsis and thrombosis[J].Cardiovasc Res,2004;61(4):671-82.
9Li C,Browder W,Kao RL.Early activation of transcription factor NF-κB during ischemia in perfused rat heart[J].Am J Physiol,1999;276(2 Pt 2):H543-52.
10Ioculano M,Squadrito F,Ahavila D,et al.Antibodies against intercelular adhension molecule 1 protect against myocardial ischemia-reperfusion injury in the rat[J].Eur J Pharmacol,1994;264(2):143-9.