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山羊microRNA研究进展

Advances in Research of Goat MicroRNA
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摘要 小RNA(micro RNA,mi RNA)是真核生物中发现的一类内源性的具有调控功能的非编码RNA,长度约20~25个核苷酸。研究表明,mi RNA参与真核生物的许多生命过程,包括个体发育、新陈代谢、细胞生长和凋亡等方面。目前,关于山羊(Capra aegagrus hircus)的mi RNA数据相对较少。文章综述了山羊mi RNA对皮肤与毛囊发育、肌肉生长发育、泌乳及生殖的调控作用,为利用mi RNA调控和改善绒山羊毛绒品质、生长性能及繁殖性能等提供理论基础和研究思路。 MicroRNA(mi RNA), a class of non-coding RNA(about 20﹣25 nt), has been found in eukaryotes and has regulatory functions. Many research results have confirmed that mi RNAs play an important role in many life processes in eukaryotes, involving the individual development, metabolism, cell growth and apoptosis, etc. At present, there are relatively few mi RNA data in goat(Capra aegagrus hircus). This article summarizes the regulation of mi RNAs in skin and hair follicle development, muscle growth and development, lactation and reproduction of goat. This review will provide theoretical basis and research insight for possible use of mi RNAs to regulate and improve the wool and cashmere quality, the growth, and reproductive performance in goat.
出处 《动物学杂志》 CAS CSCD 北大核心 2016年第1期137-147,共11页 Chinese Journal of Zoology
基金 新疆维吾尔自治区高校科研计划青年教师科研启动基金项目(No.XJEDU2011S31) 新疆师范大学博士科研启动基金项目(No.XJNUBS1101) 新疆维吾尔自治区地方公派出国留学成组配套项目(No.XJDF201327) 新疆维吾尔自治区教育厅普通本科高等学校重点实验室项目
关键词 小RNA 山羊 基因调控 MicroRNA Goat Gene regulation
作者简介 叶小芳,女,副教授:研究方向:动物学;E-mail:yxf001982@sina.com。
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