期刊文献+

运动疗法联合重组人Ⅱ型肿瘤坏死因子受体抗体融合蛋白治疗强直性脊柱炎的临床疗效 被引量:1

在线阅读 下载PDF
导出
摘要 选取收治的强直性脊柱炎患者64例,随机分为对照组和试验组。对照组予以重组人Ⅱ型肿瘤坏死因子受体抗体融合蛋白治疗,试验组予以运动疗法联合重组人Ⅱ型肿瘤坏死因子受体抗体融合蛋白治疗。比较两组治疗前后的临床疗效。治疗后,试验组所有指标均较治疗前显著改善(P<0.05),而对照组的扩胸度、Schober和BASMI与治疗前没有显著变化(P>0.05),且试验组的改良Schober试验、BASMI、ASQo L以及扩胸度显著优于对照组(P<0.05);治疗后,两组的ASAS20有效率没有统计学差异(P>0.05)。强直性脊柱炎采用运动疗法联合重组人Ⅱ型肿瘤坏死因子受体抗体融合蛋白治疗可以更有效地改善患者的机体功能、胸廓活动度和脊椎活动度,临床疗效更佳。
出处 《现代诊断与治疗》 CAS 2015年第21期4983-4984,共2页 Modern Diagnosis and Treatment
  • 相关文献

参考文献8

二级参考文献65

  • 1郝慧琴,黄烽,唐捷,邓小虎,张亚美,索塔林,方显峰.不同剂量重组人Ⅱ型肿瘤坏死因子受体-Fc融合蛋白治疗强直性脊柱炎疗效比较[J].中华风湿病学杂志,2007,11(4):202-205. 被引量:17
  • 2DOUGADOS M,VAN DER LINDEN S,LERRISALO-REPO M,et al. Suifasalazine in the treatment of spondylarthropathy: a randomized, multicenter, double-blind, placebo-controlled study [ J ]. Arthritis Rheum, 1995,38 ( 5 ) :618 - 627.
  • 3BRANDT J,LISTING J, HAIBEL H,et al. Long-term efficacy and safety of etanercept after readministration in patients with active ankylosing spondylitis [ J ]. Rheumatology, 2005,44 ( 9 ) : 342 - 348.
  • 4BOONEN A,VAN DER HEIJDE D,SEVERENS JL,et al. Markov model into the cost-utility over five years of etanercept and infliximab compared with usual care in patients with active ankylosing spondylitis [ J ]. Ann Rheum Dis,2006,65 ( 3 ) :201 - 208.
  • 5S. SZANTO+ M. ALEKSZA. Intracytoplasmic Cytokine Expression and T Cell Subset Distribution in the Peripheral Blood of Patients with Ankylosing Spondylitis [ J]. Rheumatology, 2008,35 ( 7 ) : 2372 -2375.
  • 6TAE-JONG KIM,TAE-HWAN KIM, HYUN-JOO LEE, et al. Interleukin 1 Polymorphisms in Patients with Ankylosing Spondylitis in Korea[ J]. Rheumatology ,2008,35 (7) : 1603 - 1608.
  • 7SIMON M, GERALD W. The Immune Response to Autologous Baeteroides in Ankylosing Spondylitis Is Characterized by Reduced Intrleukin 10 Production [ J ]. Rheumatology, 2009,36 ( 6 ) : 797 - 800.
  • 8Zochling J,van der Heijde D,Burgos-Vargas R,et al.ASAS/EULAR recommendations for the management of ankylosing spondylitis[J].BMJ,2006,65(4):442-452.
  • 9Gran JT,Skomsvoll JF.The outcome of ankylosing spondylitis:a study of 100patients[J].Br J Rheumatol,1997,36(7):766-771.
  • 10Dagfinrud H,Halvorsen S,Vllestad NK,et al.Exercise programs in tri-als for patients with ankylosing spondylitis:do they really have the po-tential for effectiveness?[J].Arthritis Care Res(Hoboken),2011,63(4):597-603.

共引文献49

同被引文献3

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部