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运用随机森林分析体检人群肾结石的影响因素 被引量:7

Random Forest analysis of risk factors of nephrolithiasis
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摘要 目的采用随机森林算法分析体检人群肾结石的影响因素。方法自体检人群中选取955例肾结石患者和1 670例未患肾结石者,收集各项生化指标,先利用随机森林方法进行降维,再用传统的Logistic回归对降维后的变量进行分析。结果经随机森林算法筛出8个重要性得分最高且错误率最低的变量纳入经典Logistic回归模型进行分析,最终进入Logistic回归模型的变量有性别、年龄、体质指数、收缩压、低密度脂蛋白、总胆红素。结论肾结石的发病与性别、年龄及人体多项生化指标有关。 Objective To investigate the risk factors of nephrolithiasis with Random Forest model. Methods Randomly selected patients with kidney stones 955 cases and 1670 cases not suffering from kidney stones were collected physiological and biochemical indices of each group. Then we analyzed the risk factors for kidney stones using Random Forest. Results Eight important variables,whose average importance scores were highest and whose error rates were lowest, were selected by Random Forest method. Then the logistic regression was conducted, including the variables of sex, age, BMI, SBP, LDL, TBIL. Conclusion The increase of age, BMI,SBP, and LDL are the risk factors for renal calculus, but the increase of TBIL, sex showed inhibition against renal calculus.
出处 《现代预防医学》 CAS 北大核心 2016年第1期1-3,7,共4页 Modern Preventive Medicine
基金 社会发展项目(BE2011647)
关键词 肾结石 随机森林 影响因素 Nephrolithiasis Random Forest Factors
作者简介 李苹(1989-),女,硕士,研究方向:流行病与卫生统计学 通讯作者:黄水平,E—mail:hsp@xzmc.edu.cn
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  • 1Romero V, Akpinar H, Assimos DG. Kidney stones: a global picture of prevalence, incidence, and associated risk factors [J]. Reviews inurology, 2010, 12 (2/3): e86-e96.
  • 2Evan AP. Physiopathology and etiology of stone formation in the kidney and the urinary tract [J]. Pediatric nephrology (Berlin, Germany), 2010, 25 (5): 831-841.
  • 3Breiman L. Random forests[J]. Machine Learning, 2001, 45 (1) : 5-32.
  • 4Jiang R, Tang W, Wu X, et al. A random forest approach to the detection of epistatic interactions in case-control studies [J]. BMC Bioinformatics, 2009, 10 (Suppl 1): S65.
  • 5蔡妤喆,简涛,雍继雄,王娜,赵思修,汪智慧,林威,蒋晓涓,秦德强,刘玉兰,王霞,宋媛,朱枫,文平,姜果,李扬金,罗清凤,张世勇,殷宗银,李婷,刘晓玲,刘健.青神县肾结石发病情况及影响因素调查[J].现代医药卫生,2012,28(3):356-357. 被引量:7
  • 6Maalouf NM, Sakhaee K, Parks JH, et al. Association of urinary pH with body weight in nephrolithiasis [J]. Kidney International, 2004, 65 (4): 1422-1425.
  • 7曾永红,张景莉,付小梅.肾结石与尿酸、血脂、血糖的关联[J].国际医药卫生导报,2006,12(20):21-23. 被引量:4
  • 8彭绩,周海滨,程锦泉,董时富,施侣元,张丹.深圳特区肾结石流行现况及危险因素分析[J].中华流行病学杂志,2003,24(12):1112-1114. 被引量:17
  • 9刘雪芳,曾炼坤,夏碧文.2型糖尿病伴发肾结石的危险因素[J].国际医药卫生导报,2014,20(4):517-519. 被引量:10
  • 10Daudon M, Traxer O, Conort P, et al. Type 2 diabetes increases the risk for uric acid stones [J]. Journal of the American Society of Nephrology: JASN, 2006, 17 (7): 2026-2033.

二级参考文献53

  • 1刘景铎.成年人肾结石病的病因及防治[J].人民军医,2005,48(7):407-409. 被引量:12
  • 2裘法祖.外科学[M].北京:人民卫生出版社,1995..
  • 3powell CR,Stoller ML and Schwartz BF et al.Impact of body weight on urinary electrolytes in urinary stone formers[J].Urology,2000,55(6):825-30
  • 4Bate A,Evans S. Quantitative signal detection using spontaneous ADR reporting. Pharmacoepidemiol Drug Saf,2009,18 (6) :427-436.
  • 5Hauben M,Bate A. Decision support methods for the detection of ad- verse events in post-marketing data. Drug Discov Today, 2009,14 ( 7- 8) :343-57.
  • 6Stephenson WP, Hauben M. Data mining for signals in spontaneous re- porting databases:proceed with caution. Phannacoepidemiol Drug Saf, 2007,16:359-365.
  • 7Krisztina N,Jeno R,Andrea H,et al. Tree-based methods as an alterna- tive to logistic regression in revealing risk factors of crin-biting in hor- ses. Journal of Equine Veterinary Science,2010,30 ( 1 ) :21-26.
  • 8Yoonhee K, Robert W, et al. Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects. BMC Proceedings Volume 3 Supplement 7,2009 : Genetic Anal- ysis Workshop 16.
  • 9Yah VS, Lawrence FB, et al. Application of machine learning algo- rithms to predict coronary artery calcification with a sibship-based de- sign. Genet Epidemio1,2008,32 (4) :350-360.
  • 10Mao W, Shannon K. An optimum random forest model for prediction of genetic susceptibility to complex diseases. Lecture Notes in Computer Science, 2007,4426 : 193-204.

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