摘要
目的:探讨2型糖尿病合并抑郁症的临床特点及相关危险因素。方法:选取北京市丰台区6家医疗机构636例2型糖尿病患者,对患者进行汉密尔顿抑郁量表(HAMD)测评,并填写糖尿病临床观察表,根据HAMD测评结果将患者分为糖尿病合并抑郁症组和非抑郁症组,分析对比2组的疾病相关因素及理化指标,对可能的相关因素分别进行单因素和多因素Logistic回归分析,探讨2型糖尿病合并抑郁症的危险因素。结果:636例2型糖尿病患者合并抑郁的患病人数为138人,患病率为21.7%。单因素分析发现糖尿病病程、并发症、运动锻炼、胰岛素治疗、Hb A1c在2组之间差异有统计学意义(P<0.05)。Logistic回归分析显示:并发症、缺乏运动锻炼、高Hb A1c均是糖尿病合并抑郁症的危险因素(P<0.05)。结论:Hb A1c高、存在多种并发症及缺乏运动锻炼的2型糖尿病患者是抑郁症的高发人群,应积极对其进行心理疏导,鼓励积极锻炼,控制血糖,必要时进行抑郁症筛选。
Objective： To explore the clinical characteristic and relevant risk factors of type 2 diabetes with depression. Methods：A total of 636 type 2 diabetes patients from Dong Fang hospital and five community health service centers,were evaluted Hamilton Depression Rating Scaleand diabetes clinical observation tableat the same time. These patients were divided into the depression group and simple group. Compared various factors associated with disease and physical and chemical indicators. Logistic regression analysis was applied to investigate the risk factors for type 2 diabetes with depression. Results： The 636 diabetes,138（ 21. 7%）were type 2 diabetes with depression. Single facor analysis revealed that the duration of 2 diabetes、the number of complications,exercise、Insulin therapyand glycosylated hemoglobin（ Hb A1c） existsignificantdifferences between the two groups（ P 0. 05）. Logistic regression analysis shows that the number of complications,exercise,Hb A1 c were the risk factors of type 2 diabetes with depression patients（ P 0. 05）. Conclusion： Psychological counseling should be taken to the patient with complications,no exercise,and high Hb A1 c levels.
出处
《世界中医药》
CAS
2015年第10期1607-1610,共4页
World Chinese Medicine
基金
首都医学科研发展基金项目(编号:SF-2007-Ⅲ-09)
丰台区卫生系统科学研究项目
关键词
糖尿病
2型
抑郁症
危险因素
Diabetes Mellitus
Type 2
Depression
Risk Factors
作者简介
龙泓竹（1986-），女，博士研究生，研究方向：中医药防治糖尿病及并发症，E-mail：longhongzhu@126．com
通信作者：杨晓晖（1968-），男，博士，教授，主任医师，博士研究生导师，研究方向：中医药防治糖尿病及并发症，E-mail：yxh0616@126．com.
