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儿童闭塞性细支气管炎的研究进展 被引量:20

Progress of bronchiolitis obliterans in children
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摘要 闭塞性细支气管炎(BO)是以小呼吸道阻塞和气流受限为特点的慢性气流阻塞综合征。儿童BO多继发于下呼吸道的严重感染,其发生发展与炎症和免疫反应有关。因肺活检难度大,目前BO的诊断还是依赖于患儿的临床表现、肺功能和高分辨率CT(HRCT)检查。肺部HRCT是非常有意义的非创伤性检查,值得推广。目前BO尚无公认的有效治疗,早期诊治可阻断疾病的进程。因对本病的认识不足,未能引起医师和家长足够的重视,病程迁延,预后差。 Bronchiolitis obliterans(BO) is chronic airflow obstruction syndrome characterized by small airway obstruction and airflow limitation. In children, BO is secondary to severe infection of respiratory tract, and its development is related with inflammation and immune response. At present, the diagnosis of BO mainly is depended on the clinical manifestation,lung function and examination results of high resolution computed tomography (HRCT) because of difficulty of lung biopsy. Pulmonary HRCT is a non - invasive examination, and worthy of generalization. Currently, BO has no accepted effective treatment, early diagnosis and treatment can block the progression of BO. Due to lack of realization of BO, doctors and parents fail to give enough attention, BO has a prolonged course and very poor prognosis.
作者 夏利平 姜毅
出处 《中华实用儿科临床杂志》 CSCD 北大核心 2015年第22期1754-1757,共4页 Chinese Journal of Applied Clinical Pediatrics
关键词 闭塞性细支气管炎 马赛克灌注征 纤维化 肺功能 Bronchiolitis obliterans Mosaic perfusion sign Fibrosis Lung function
作者简介 通信作者:姜毅,Email:jiangyiwd@163.com
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