摘要
目的比较保乳术与改良根治术在早期乳腺癌治疗中的效果。方法回顾性分析重庆市龙坡区第五人民医院2011年3月~2013年3月收治的80例早期乳腺癌患者的临床资料。根据手术方式的不同将患者分为改良根治术组（42例）和保乳术组（38例）。改良根治术组行乳腺癌改良根治术,保乳术组采用保乳手术治疗。观察记录两组患者手术时间、术中出血量及住院时间。采用乳腺美容评估标准评价保乳术组患者术后乳房美容效果。随访患者术后无病生存、局部复发、远处转移及失访/死亡情况,并采用健康状况调查简表（SF-36）评价患者术后生命质量。结果保乳术组手术时间及住院时间明显短于改良根治术组,术中出血量明显少于改良根治术组,差异均有统计学意义（均P〈0.05）。保乳术组术后美容优良率达94.74%。术后随访发现,两组无病生存率、局部复发率、远处转移率及失访/病死率比较,差异均无统计学意义（均P〉0.05）。术后保乳术组患者SF-36量表生理功能、生理职能、躯体疼痛、总体健康、生命活力、社会功能、情感职能、心理健康和平均得分均显著高于改良根治术组,差异均有统计学意义（均P〈0.05）。结论保乳术与改良根治术治疗早期乳腺癌的效果相近,且与改良根治术比较,保乳术能明显缩短手术时间、住院时间,减少术中出血量,且术后美容效果好,能显著改善术后生命质量,可作为早期乳腺癌的首选术式。
Objective To compare the effect of breast conserving surgery and modified radical operation in the treatment of early breast cancer. Methods From March 2011 to March 2013, in the Fifth People＇s Hospital of Longpo District in Chongqing City, the clinical data of 80 patients with early breast cancer admitted to were analyzed retrospectively, according to the different surgical method, the patients were divided into modified radical operation group（42 cases）and breast conserving surgery group（38 cases）. The modified radical operation group was taken modified radical operation, the breast conserving surgery group was taken breast conserving surgery. The operation time, intraoperative blood loss and length of the two groups were observed and recorded. The cosmetic result of postoperative breast in breast conserving surgery group was evaluated by breast beauty evaluation criteria. The conditions of postoperative disease free survival, local recurrence, distant metastasis and death were followed up. The postoperative quality of life was evaluated by health questionnaire（SF-36）. Results The operation time and length of stay in breast conserving surgery group was significantly shorter than those of modified radical operation group, the intraoperative blood loss was significantly less than that of modified radical operation group（all P〉0.05）. The excellent and good rate of postoperative beauty in breast conserving surgery group reached to 94.74%. Postoperative follow-up found that the rates of disease free survival, local recurrence, distant metastasis and lose visit/death between the two groups had no statistically significant differences（all P〈0.05）. The scores of postoperative physiological function, physiological role, body pain, general health,vigour of life, social function, role emotional, mental health and average score of SF-36 in breast conserving surgery group were all significantly higher than those of modified radical operation group（all P〈0.05）. Conclusion Breast conserving surgery and modified radical operation in the treatment of early breast cancer have similar effects. Compared with modified radical operation, breast conserving surgery can significantly shorten operation time and length of stay,reduce intraoperative blood loss, and the postoperative cosmetic result is good, which can improve the postoperative quality of life and can be as the preferred operation of early breast cancer.
出处
《中国医药导报》
CAS
2015年第32期100-103,共4页
China Medical Herald
关键词
保乳术
改良根治术
早期乳腺癌
效果
Breast conserving surgery
Modified radical operation
Early breast cancer
Effect
