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非霍奇金淋巴瘤治疗现状 被引量:11

Current treatment of non Hodgkin lymphoma
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摘要 淋巴瘤是原发于淋巴系统的恶性肿瘤,分为霍奇金淋巴瘤和非霍奇金淋巴瘤。其中非霍奇金淋巴瘤(non-Hodgkin lymphoma,NHL)占整个淋巴瘤的90%。NHL种类繁多,不同的淋巴瘤有不同的治疗原则。目前常用的治疗指南有欧洲肿瘤内科学会(European Society for Medical Oncology)指南、美国国立综合癌症网络(National Comprehensive Cancer Network)诊治指南和我国的淋巴瘤诊治规范。我们将结合这3个指南对NHL的治疗现状进行介绍。 Lymphoma is a malignant tumor of the lymphatic system which can be divided into Hodgkin lymphoma and non Hodgkin lymphoma(NHL).The NHL accounts for 90% of total lymphomas.NHL is a heterogeneous group of lymphoproliferative disorders including different subtypes which have different therapeutic principles.The European Society for Medical Oncology guidelines,National Comprehensive Cancer Network guidelines of the United States and the diagnosis and treatment guidelines of lymphoma of China are the primary guidelines at present in our country.The following discussion will focus on the current treatment of NHL combining these three guidelines.
出处 《临床荟萃》 CAS 2015年第10期1110-1119,共10页 Clinical Focus
关键词 淋巴瘤 非霍奇金 诊断 治疗 lymphoma non-hodgkin diagnosis therapy
作者简介 通信作者:魏旭东,Email:weixudong63@126.com
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参考文献64

  • 1Friedberg JW,Byrtek M,Link BK,et al.Effectiveness of first-line management strategies for stage I follicular lymphoma:analysis of the National LymphoCare Study[J].J Clin Oncol,2012,30(27):3368-3375.
  • 2Michallet AS,Lebras LL,Bauwens DD,et al.Early stage follicular lymphoma:what is the clinical impact of the first-line treatment strategy?[J].J Hematol Oncol,2013,6:45.
  • 3Nastoupil L,Sinha R,Byrtek M,et al.A Comparison of the Effectiveness of First-Line Chemoimmunotherapy Regimens for Follicular Lymphoma(FL)Used in the United States[J].ASH Annual Meeting Abstracts,2011,118:97.
  • 4Federico M,Luminari S,Dondi A,et al.R-CVP versus R- CHOP versus R-FM for the initial treatment of patients with advanced-stage follicular lymphoma:results of the FOLL05 trial conducted by the Fondazione Italiana Linfomi[J],J Clin Oncol,2013,31(12):1506-1513.
  • 5Rummel MJ,Niederle N,Maschmeyer G,et al.Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas:an open-label,multicentre,randomised,phase 3 non-inferiority trial[J].Lancet,2013,381(9873):1203-1210.
  • 6Salles G,Seymour JF,Offner F,et al.Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy(PRIMA):a phase 3,randomised controlled trial[J]Lancet,2011,377(9759):42-51.
  • 7Rohatiner AZ,Gregory WM,Peterson B,et al.Meta-analysis to evaluate the role of interferon in follicular lymphoma[J].J Clin Oncol,2005,23(10):2215-2223.
  • 8Baldo P,Rupolo M,Compagnoni A,et al.Interferon-alpha for maintenance of follicular lymphoma[J],Cochrane Database Syst Rev,2010,20(1):CD004629.
  • 9Schaffel R,Hedvat CV,Teruya-Feldstein J,et al.Prognostic impact of proliferative index determined by quantitative image analysis and the International Prognostic Index in patients with mantle cell lymphoma[J].Ann Oncol,2010,21(1):133-139.
  • 10Geisler CH,Kolstad A,Laurell A,et al.Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue:a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group[J].Blood,2008,112(7):2687-2693.

二级参考文献33

  • 1孙燕,石远凯.临床肿瘤内科手册[M].5版.北京:人民卫生出版社,2011:135-146.
  • 2Korl AD, le Gessie S, Snijder S, et al. Primary extranodal non- Hodgkin' s lymphoma (NHL): the impact of alternative defini- tions tested in the Comprehensive Cancer Centre West popula- tion-based NHL registry. Ann Oncol, 2003, 14:131-139.
  • 3Li XQ, Li GD, Gao ZF, et al. The relative frequencies of lympho- ma subtypes in China: a nationwide study of 10002 cases by the Chinese Lymphoma Study Group. Ann Oncol, 2011, 22 Suppl 4: ivl41.
  • 4Fisher RI, Gaynor ER, Dahlberg S, et al. Comparison of a stan- dard regimen (CHOP) with three intensive chemotherapy regi- mens for advanced non-Hodgkin' s lymphoma. N Engl J Med, 1993, 328:1002-1006.
  • 5Reyes F, Lepage E, Ganem G, et al. ACVBP versus CHOP plus radiotherapy for localized aggressive lymphoma. N Engl J Med, 2005, 352:1197-1205.
  • 6Coiffier B, Thieblemont C, Van Den Neste E,et ah Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemother- apy in DLBCL patients: a study by the Grouped' Etudes des Lymphomes de 1' Adulte. Blood, 2010, 116:2040-2045.
  • 7Seki R, Ohshima K, Nagafuji K, et al. Rituximab in combination with CHOP chemotherapy for the treatment of diffuse large B cell lymphoma in Japan: a retrospective analysis of 1,057 cases from Kyushu Lymphoma Study Group. Int J Hematol, 2010, 9 I: 258-266.
  • 8Sehn LH, Donaldson J, Chhanabhai M, et al. Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia. J Clin Oncol, 2005, 23:5027-5033.
  • 9Habermama TM, Weller EA, Morrison VA, et al. Rituximab- CHOP versus CHOP alone or with maintenance rituximab in old- er patients with diffuse large B-cell lymphoma. J Clin Oncol, 2006, 24:3121-3127.
  • 10Tilly H, Dreyling M. ESMO Guidelines Working Group. Diffuse large B-cell non-Hodgkin' s lymphoma: ESMO clinical recom- mendations for diagnosis, treatment and follow-up. Ann Oncol, 2008, Suppl 2:ii67-69.

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  • 1张彤,任国平,王佩.苯丁酸氮芥单药治疗复发难治性低度恶性非霍奇金淋巴瘤37例临床观察[J].白血病.淋巴瘤,2006,15(6):446-448. 被引量:2
  • 2王跃,麦涛,刘明方,陈淑惠.双歧杆菌脂磷壁酸对凋亡抑制因子survivin表达及其调控基因的影响[J].中华肿瘤杂志,2007,29(5):325-328. 被引量:15
  • 3Orlowski R Z,Voorhees P M,Garcia R A,et al.Phase I trial ofthe proteasome inhibitor bortezomib and pegy Lated liposomal doxorubi-ein in patients with advanced hematologic malignancies[J].Blood,2005,105(8):3058-3065.
  • 4Visani G,Guiducci B,D’ Adamo F,et al.Cyclophosphamide,pegylated liposome doxorubicin,vincristine and prednisone(GDOP) plusrituximab is effective and well tolerated in poor performancestatus elderly patients with Non-Hodgkin lymphoma[J].Leukemia lymphoma,2005,46(3):477-479.
  • 5Illidge T,Specht L,Yahalom J,et al.Modern radiation therapy for nodal non-hodgkin lymphoma-target definition and dose guidelines from the international lymphoma radiation oncology group[J].Int J Radiat Oncol Biol Phys,2014,89(1):49-58.
  • 6Strobbe L,Van der Schans,S A,Heijker S,et al.Evaluation of a panel of expert pathologists:review of the diagnosis and histological classification of Hodgkin and non-Hodgkin lymphomas in a population-based cancer registry[J].Leukemia and lymphoma,2014,55(5):1018-1022.
  • 7Hagemeister F B,Rodriguez M A,Deitcher S R,et al.Long term results of a phase 2 study of vincristine sulfate liposome injection(MarqiboR) substituted for non-liposomal vincristine in cyclophosphamide,doxorubicin,vincristine,prednisone with or without rituximab for patients with untreated aggressive non-Hodgkin lymphomas[J].Blood,2013,122(21):3033.
  • 8Deng Z,Yan F,Jin Q,et al.Reversal of multidrug resistance phenotype in human breast cancer cells using doxorubicin-liposome-microbubble complexes assisted by ultrasound[J].J Control Release,2014,174(1):109-116..
  • 9闫轶鹏.吡柔比星为主联合化疗方案治疗老年非霍奇金淋巴瘤[J].中国临床实用医学,2010(2):151-152. 被引量:6
  • 10王彦艳,张晋林,王椿,王欣,吴德沛,梁辉,朱军,李军民,沈志祥.CTOP与CHOP方案治疗初治侵袭性非霍奇金淋巴瘤患者疗效分析——一项前瞻、开放、随机、多中心临床研究[J].中华血液学杂志,2010,31(10):649-653. 被引量:13

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