摘要
目的探讨低频重复经颅磁刺激对帕金森病患者功能障碍及情感障碍的影响。方法选择2014年1～12月帕金森病患者50例为研究对象，分为研究组和对照组各25例。研究组在常规治疗基础上给予低频重复经颅磁刺激治疗，对照组仅给予常规治疗。比较两组患者治疗后运动功能障碍及情感障碍。结果两组治疗后HAMD评分比较差异有统计学意义，研究组显著低于对照组（R0．05），HAMA比较差异无统计学意义（P〉0．05）；治疗后研究组HAMD评分较治疗前显著下降（P〈0．05）。研究组治疗后UPDRS总分及I、Ⅱ、Ⅲ级别评分均显著下降（P〈0．01）；研究组治疗后UPDRS总分及I、Ⅱ、Ⅲ级别评分均显著低于对照组（P〈0．01）。结论在常规药物治疗基础上给予低频重复经颅磁刺激能够显著改善患者功能障碍以及抑郁障碍，对患者焦虑障碍改善不明显。
Objective To discuss effect of rTMS on dysfunction and mood disorders for Parkinson＇s disease. Methods Selected 50 cases from Jan to Dec 2014 with Parkinson＇s disease and they were divided into study group and control group, with 25 cases of each group. Study group was treated with rTMS based on conventional treatment, and control group was treated with conventional treatment. Dysfunction and mood disorders after treatment of two groups were com- pared. Results After treatment, HAMD scores of study group was lower than control group （P〈0.05）, and HAMA scores showed no significant difference between two groups （P〉0.05）; HAMD scores of study group after treatment was lower than before treatment（P〈0.05）. After treatment, UPDRS score and scores of I, Ⅱ, Ⅲ of study group were lower（P〈0.01）; After treatment, UPDRS score and scores of I, Ⅱ, Ⅲ of study group were lower than control group（P〈0.01）. Con- clusion rTMS for Parkinson＇s disease based on conventional treatment can improve dysfunction and depression, but no obvious improvement in patients with anxiety disorders.
出处
《中国现代医生》
2015年第29期61-63,共3页
China Modern Doctor
基金
河南省医学科技攻关计划指导性计划项目(201404020)
