摘要
目的 探讨非综合征唇腭裂的发病特点,为治疗提供依据.方法 收集1435例非综合征唇腭裂病例,对患者的性别、疾病部位、血型、伴发畸形、遗传史等进行回顾性分析.结果 1435例中,单纯唇裂397例（27.67％）,单纯腭裂655例（45.64％）,唇裂伴腭裂383例（26.68％）.男性801例（55.82％）,女性634例（44.18％）.单纯唇裂组男性60.20％（239例）多于女性39.80％（158例）,左侧57.43％（228例）多于右侧27.96％（111例）,左侧多于双侧14.61％（58例）,右侧多于双侧;唇裂伴腭裂组男性78.33％（300例）多于女性21.67％（83例）,左侧41.50％（159例）多于右侧28.20％（108例）,左侧多于双侧30.29％（116例）;单纯腭裂女性60.00％（393例）多于男性40.00％（262例）;AB型血在单纯唇裂组患者的比例（28/369）高于单纯腭裂组（28/627）;差异有统计学意义（P＜0.05）.合并畸形者占5.09％（73例）,其中伴发先天性心脏病患者数量最多2.51％（36例）.单纯唇裂、单纯腭裂与唇裂伴腭裂病例间父系、母系、同胞来源的遗传史差异均无统计学意义（P＞0.05）.结论 单纯唇裂患者,男性多于女性,左侧多于右侧,单侧多于双侧;唇裂伴腭裂患者,男性多于女性,左侧多见;单纯腭裂患者中女性发病高于男性;单纯唇裂患者AB型血比例高于单纯腭裂患者.
Objective To investigate the characteristics of patients with non-syndromic cleft lip with or without cleft palate （NSCL/P）,and to provide the basis for the treatment.Methods 1435 cases of NSCL/P were collected from January 2012 to December 2014.Characteristics of the gender,type and side,blood type,associated malformation,genetic history of the patients were analyzed retrospectively.Results In the 1435 cases,397 cases （27.67％） presented with cleft lip,655 cases （45.64％） with cleft palate,and 383 cases （26.68％） with cleft lip and palate.801 （55.82％） were male,and 634 （44.18％） were female.In cleft lip,male 60.20％ （n=239） were more than female 39.80％ （n=158）;left side was 57.43％ （n=228） more than right 27.96％ （n=111） and the right were more than bilateral 14.61％ （n=58）.In cleft lip and palate,male 78.33％ （n=300） were more than female 21.67％ （n=83）,left 41.51％ （n=159） were more than right 28.20％ （n=108） and bilateral 30.29％ （n=116）.In cleft palate,female 60.00％ （n=393） were more than male 40.00％ （n=262）.Blood type AB with cleft lip （28/369） were higher than ones with cleft palate （28/627）.All of the differences were statistically significant （P＜0.05）.5.09 ％ （n =73） patients with malformation were found out of 1435 cases.The patients with congenital heart disease （n=36,2.51％） was the largest number of total deformity.Conclusions In patients with cleft lip,male is more than female;left side is more than right;unilateral clefts are higher that bilateral ones.In cleft lipand palate,male were more than female,left side were higher.In cleft palate,female were more than male.Blood type AB with cleft lip is higher than that of cleft palate.
出处
《中华医学美学美容杂志》
2015年第5期284-286,共3页
Chinese Journal of Medical Aesthetics and Cosmetology
基金
广州市医药卫生科技项目重点项目（20121A021013）
关键词
唇裂
腭裂
唇裂伴腭裂
统计分析
Cleft lip
Cleft palate
Cleft lip and palate
Statistical analysis
作者简介
通信作者：王洪涛，E—mail：wht199902@163．com
