摘要
目的观察丙泊酚、依托咪酯联合地佐辛在无痛人流术中的镇痛效果,寻求一种安全有效的人工流产术的镇痛方法。方法选择无痛人流术的患者120例,随机分为三组:丙泊酚组(P组)、依托咪酯组(E组)、丙泊酚复合依托咪酯组(C组),每组40例。三组均使用地佐辛镇痛。比较三组间麻醉前、麻醉后及清醒时BP、HR、Sp O2值,睁眼时间、恢复行走时间及不良反应情况。结果与E组和C组比较,P组低氧血症、低血压和注射痛发生率高(P<0.05)。E组术中肌震颤、术后恶心呕吐明显高于P组和C组(P<0.05)。三组麻醉效果及苏醒时间无明显差异(P>0.05)。结论小剂量地佐辛诱导后联合应用丙泊酚和依托咪酯麻醉,对无痛人流患者的呼吸、循环系统抑制轻微,不良反应发生少,是一种安全有效的人工流产术的镇痛方法。
Objective To observe the analgesic effect of propofol, etomidate combined with dezocine in painless artificial abortion, and seek a safe and effective analgesia method. Methods 120 cases of painless artificial abortion were randomly divided into 3 groups： propofol group （Group P）, etomidate group （Group E）, propofol and etomidate group （Group C）, with 30 cases in each group. The 3 groups were all using dezocine analgesia. The BP, HR, SpO2, time of opening eyes, walking recovery time and adverse effects before anesthesia, after anesthesia and after awake were recorded and compared between 3 groups. Results The incidences of hypoxia, hypotension and injection pain in Group P were higher than those in Group E and Group C （P 〈0.05）. The rates of muscle tremor during operation and postoperative nausea and vomiting were significantly higher than those of Group P and Group C （P 〈0.05）. No significant difference was found among 3 groups in the anesthesia effect and recovery time （P 〉0.05）. Conclusions The use of propofol, etomidate combined with dezocine used in painless artificial abortion is a safe and effective analgesia method, which has slight inhibition for respiratory and circulatory system, and fewer complications.
出处
《临床医学工程》
2015年第9期1185-1186,共2页
Clinical Medicine & Engineering
关键词
人工流产
丙泊酚
依托咪酯
地佐辛
镇痛
Artificial abortion
Propofol
Etomidate
Dezocine
Analgesia
作者简介
黄芳（1968-），女，湖北潜江人，主治医师，本科学历，从事临床麻醉工作。
