期刊文献+

2012年北京市密云县健康人群麻疹抗体水平监测 被引量:1

Monitoring on antibody level of measles in healthy population in Miyun county of Beijing in 2012
在线阅读 下载PDF
导出
摘要 目的了解2012年北京市密云县健康人群的麻疹抗体水平。方法按照地理位置、人口构成随机抽取密云县9个接种单位的10个行政村(居委会)为监测点,选择在当地连续居住6个月以上的健康人群,分10个年龄组,共采集静脉血标本268份,男、女性别比例在0.8~1.2之间。结果此次麻疹抗体阳性率为88.43%;几何平均滴度(GMT)为1532.4IU/L。不同年龄抗体阳性率差异有统计学意义(χ^2=126.405,P=0.000),不同年龄的GMT差异有统计学意义(F=5.337,P=0.000)。结论密云县健康人群麻疹抗体阳性率、GMT总体保持在较高水平,0~7月龄婴儿麻疹抗体的低阳性率反应出部分成人抗体较低,因而小月龄婴儿获得的母传抗体随之较低。 Objective To understand antibody level of measles in healthy population in Miyun county of Beijing in 2012. Methods According to the geographical location and demographic,10 administrative villages (neighborhood committees) in Miyun county were randomly celected for monitoring. Healthy people who had lived in the local continuously for 6 months or more were recruited and divided into 10 groups. Sex ratio of male to female is 0. 8 to 1.2. A total of 268 venous blood samples were collected. Results Positive rate of measles antibody was 88.43% ; The GMT was 1532.4 IU/L. The difference of antibody positive rate between different age group was statistically significant (chi-square = 126.405, P = 0. 000) , the difference of GMT between different age group was statistically significant ( F = 5. 337, P = 0.000). Conclusion Measles antibody positive rate and GMT in healthy people in Miyun county remains generally at a higher level, low positive rate of measles antibodie in group of 0 to 7 months baby suggests that antibody level in some adult is low, therefore babies get less antibody from their mother.
出处 《首都公共卫生》 2015年第4期176-178,共3页 Capital Journal of Public Health
关键词 麻疹抗体 阳性率 几何平均滴度 健康人群 Measles antibody Positive rate Geometric average degree Healthy people
作者简介 通信作者:李思遥,E—mail:siyao1108@163.com
  • 相关文献

参考文献4

二级参考文献26

  • 1施燕,胡家瑜,汤素文,吴维寿,许文忠.上海市麻疹、流行性腮腺炎、风疹抗体水平调查分析[J].上海预防医学,2004,16(8):378-379. 被引量:39
  • 2吴红宇.健康人群风疹抗体水平监测及风疹疫苗免疫效果观察[J].咸宁学院学报(医学版),2005,19(2):108-109. 被引量:5
  • 3Lee MS, Nokes DJ, Hsu HM, et al. Protective titres of measles neutralising antibody [J]. J Med Virol, 2000, 62(4):511-517.
  • 4Ma Yi-lin. Infectious diseases [M]. Shanghai: Shanghai scientific & Technical Publishers, 2005,76-90 (In Chinese).
  • 5Miyamura K, Sato TA, Sakae K, et al. Comparison of gelatin particle agglutination and hemagglutination inhibition tests for measles seroepidemiology studies [J]. Arch Viorl, 1997, 142(10): 1963-1970.
  • 6Griyn DE. Measles virus. In: Knipe DM, Howley PM (eds) Measles virus in Welds virology. Philadelphia; Lippincott, Williams & Wilkins, 2001, 1401-1441.
  • 7Naniche D, Varior-Krishnan G, Cervoni F, et alHuman membrane cofactor protein (CD46) acts as a cellular receptor for measles virus[J]. J Virol, 1993, 67(10): 6025-6032.
  • 8Markowitz LE, Katz SL. Measles vaccine. In: Plotkin SA, Mortimer EA Jr (cds) Vaccines, 2nd cdn. Philadelphia; Saundcrs, 1994, 229-276.
  • 9van den Hof S, van Gageldonk-Lafeber AB, van Binnendijk RS, et al. Comparison of measles virus-specific antibody titres as measured by enzyme-linked immunosorbent assay and virus neutralisation assay [J]. Vaccine, 2003, 21 (27-30):4210-4214.
  • 10Cohen B J, Party RP, Doblas D, et al. Measles immunity testing: comparison of two measles IgG ELISAs with plaque reduction neutralisation assay [J]. J Virol Methods, 2006, 131 (2):209-212.

共引文献74

同被引文献3

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部