摘要
目的:探讨晚期肺癌患者应用益气化瘀法配合化疗治疗效果。方法:本组79例患者根据随机数字表法随机分为观察组(n=42)和对照组(n=37)。观察组采用益气化瘀法联合化疗治疗,对照组单用化疗方案治疗。对比分析治疗前后2组疗效、生活质量评价、免疫功能指标水平变化等。结果:观察组患者的总有效率(54.76%,23/42)显著高于对照组(32.43%,12/37),差异有统计学意义(P<0.05);观察组卡氏评分提高率显著高于对照组,而降低率显著低于对照组,差异均具有统计学意义(P<0.05);观察组CD3+、CD4+、CD4+/CD8+显著低于对照组,CD8+显著高于对照组,差异均具有统计学意义(P<0.05)。结论:晚期肺癌患者应用益气化瘀法配合化疗效果显著,具有重要临床意义。
OBJECTIVE：To investigate the efficacy of Tonifying Qi and Removing Blood Stasis Therapy plus chemotherapy for advanced lung cancer.METHODS：79 patients with advanced lung cancer were randomly assigned to either observation group （ n=42 ） treated with tonifying Qi and removing blood stasis therapy plus chemotherapy or control group （n=37） treated with chemotherapy alone.The treatment efficacy, the quality of life, and the level of immune indicators in the two groups were followed.RESULTS：The total response rate was significantly higher in the observation group than in the control group [47.62%（23/42） vs.32.43%（12/37）, P〈0.05]; the proportion of patients showing KPS score increase in the observation group was significantly higher than in the control group, yet the proportion of patients showing KPS score decrease in the observation group was significantly lower than in the control group （ P〈0.05 ）; the levels of CD3 ＋, CD4 ＋, CD4 ＋/CD8 ＋ were significantly lower while the CD8 ＋level was significantly higher in the observation group than in the control group （ P〈0.05 ） .CONCLUSIONS：The application of tonifying Qi and removing blood stasis therapy plus chemotherapy for advanced lung cancer achieved remarkable efficacy, which thus is of great clinical significance.
出处
《中国医院用药评价与分析》
2015年第6期732-734,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
肺肿瘤/中医药疗法
药物疗法
益气化瘀法
Lung neoplasms/TCM therapy
Drug therapy
Method of supplementing Qi and removing blood stasis
作者简介
主治医师。研究方向：中医药治疗中晚期实体瘤的优势。E-mail：mgc312@126．com
