摘要
目的研究山楂提取物的质量控制方法。方法通过薄层色谱法、滴定法、紫外分光光度法和高效液相特征色谱法对山楂提取物进行质量控制研究。结果薄层色谱中供试品与对照药材在相同的位置上显相同颜色斑点。滴定法测得有机酸含量大于15%,紫外法测得总黄酮含量大于8%。高效液相特征图谱呈现5个色谱峰,各色谱峰与参照物峰的相对保留时间在规定值的±5%范围内。结论该研究建立的方法可用于山楂提取物的质量控制。
Objective To research a method for the quality control of Shanzha（ hawthorn） extracts. Methods The quality control of extracts from Shanzha was carried out through TLC,titration,UV and HPLC-FP. Results The experimental sample and reference herb in TLC showed the same colored spots in the same position. Organic acid content by titration was more than 15%,total flavonoid content by UV was more than 8%; HPLC-FP exhibited five characteristic peaks,the relative retention time of each peak was within the range of ± 5% of the reference value. Conclusion The method can be used for the quality control of Shanzha（ hawthorn） extracts.
出处
《药学研究》
CAS
2015年第7期387-390,共4页
Journal of Pharmaceutical Research
基金
山东省中医药科技发展计划项目(No.2013-226)
作者简介
王玉团，男，主管药师，研究方向：中药分析，E—mail：13964175431@163．com
