摘要
目的通过分析单、双份机采血小板捐献者捐献前、后血常规参数的变化,评价捐献双份机采血小板的效率和安全性。方法随机抽取2013年6月至2014年6月在深圳市血液中心单、双份机采血小板捐献者各50例,应用血细胞计数仪分别检测机采前、后捐献者血常规主要参数水平,并对献血前、后主要参数水平进行对比分析。结果单、双份机采血小板前、后,外周血白细胞计数(WBC)比较,差异无统计学意义(P>0.05),而血红蛋白浓度(Hb)、外周血红细胞计数(RBC)、血细胞比容(Hct)、血小板计数(Plt)比较,差异均有统计学意义(P<0.05);单、双份机采血小板前,WBC、Hb、RBC、Hct、Plt比较,差异均无统计学意义(P>0.05);单、双份机采血小板后,WBC、Hb、RBC、Hct比较,差异均无统计学意义(P>0.05),而二者Plt比较,差异有统计学意义(P<0.05)。单、双份机采血小板合格率均达到100%,且献血者无不适反应。结论定期双份机采血小板对献血者是安全的,可以提高血小板采集效率,但不会明显影响献血者血常规各主要参数的水平。
Objective To evaluate the efficiency and safety of double apheresis platelets by analyzing the changes of blood routine parameters results before and after single and double apheresis platelet in donors. Methods Each 50 donors of single and double apheresis platelet were respectively extracted in the Shenzhen Municipal Blood Center from June 2013 to June 2014 and the levels of blood routine main parameters were detected by the blood counting instrument before and after double a- pheresis platelets. The obtained data were performed the contrastive analysis by the SPSS software. Results The peripheral blood WBC count had no statistical difference between before and after single and double apheresis platelet （P〉0.05） ,while Hb concentration, peripheral red blood cell （RBC） count, Hct and Pit had statistical differences （P〈0.05） ; WBC, Hb, RBC, Het and Pit before single and double apheresis platelets had no statistical differences （P〉0.05） ;WBC ,Hb ,RBC and Hct after single and double aphere sis platelets also had no statistical differences （P〉0.05）, but Plt had statistical difference between single and double apheresis platelet （P〈0.05）. The qualification rate of single and double apheresis platelet reached 100%, moreover the donors had no uncom- fortable reactions. Conclusion The double apheresis platelet at regular interval is safe for blood donors and can increase the efficiency of platelets collection without obviously affecting the levels of blood routine main parameters in the blood donors.
出处
《现代医药卫生》
2015年第14期2098-2100,共3页
Journal of Modern Medicine & Health
基金
深圳市科技研发资金支持项目(JCYJ20140416122812036)
关键词
血样采集
供血者
白细胞
血小板
血小板计数
血液学试验
Blood specimen collection
Blood donors
Leukocytes
Blood platelets
Platelet count
Hematologic tests
作者简介
伍娟（1980-），女，广东兴宁人，主管护师，主要从事血小板采集及相关安全性研究；E-mail：s1213@21cn.com。
通讯作者：孙雄飞（E-mail：sunxiongfei@yeah．net）。
