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恶性肿瘤术后合并不孕症患者经体外受精-胚胎移植治疗获妊娠3例报道并文献复习

Successful pregnancy in women with infertility following surgeries for gynecological malignancies: report of 3 cases and literature review
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摘要 探讨恶性肿瘤术后合并不孕症患者经体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)治疗的可行性及治疗结局。3例妇科恶性肿瘤术后合并不孕症患者行超促排卵周期IVF-ET,治疗后3例患者均成功获得临床妊娠,无肿瘤复发。由于妇科恶性肿瘤治疗可对女性患者的卵巢储备功能造成严重影响,因此对于恶性肿瘤术后合并不孕症患者,应采取积极助孕治疗。 We report 3 cases of successful pregnancies in women with a history of surgeries for gynecological malignancies and postoperative infertility, achieved by in vitro fertilization- embryo transfer(IVF- ET) with controlled ovarian hyperstimulation.All the 3 patients had clinical pregnancies without cancer recurrence. In such cancer survivors with infertility, the ovarian reserve is severely impaired by cancer therapies and assisted reproductive techniques should be the primary option.
出处 《南方医科大学学报》 CAS CSCD 北大核心 2015年第6期838-843,共6页 Journal of Southern Medical University
基金 国家自然科学基金(81170574)~~
关键词 生育力 恶性肿瘤 生殖技术 辅助 不孕症 卵巢储备功能 卵巢低反应 malignant neoplasms reproductive techniques assisted infertility ovarian reserve poor ovarian response
作者简介 作者简介:王楠,博士研究生,E—mail:wang_nan_lucky@163.com 通信作者:陈士岭,主任医师,教授,博导,电话:020.62787604,E-mailchensl_92@163.com
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  • 1Trimbos JB, Vergote L, Bolis G, et al. Impact of adjuvant chemotherapy and surgical staging in early stage ovarian eanc-er. EORTC adjuvant chemotherapy in ovarian neoplasm trial. J Nati Cancer Inst, 2003, 95: 113 - 125.
  • 2Tilly JI., Kolesniek RN. Sphingolipids apoptosis cancer treatments and the ovary investigating a crime against female fertility. Bioehim Biophys Acta, 2002, 1585 : 135 - 138.
  • 3Blumenfeld Z, Dann E, Avivi I, et al. Fertility after treatment for Hodgkins disease. Ann Oneol, 2002, 13 (Sup11): 188 - 147.
  • 4Shamberger RC, Sherings P,J, Ziegler JL, et al. Effects of postoperative adjuvant chemotherapy and radiotherapy on ovarian function in women undergoing treatment for soft tissue sarcoma. J Natl Cancer Inst, 1981, 67: 1213- 1218.
  • 5Bines J, Oleske DM, Cobleigh MA. Ovarian function in pre- menopausal women treated with adjuvant chemotherapy for breast cancer. Clin Oncol, 1996, 14 : 1718-1729.
  • 6Wallace WHB, Shalet SM, Crowne EC, et al. Gonadal dys- function due to cisplatinum. Med Pediatr Oncol, 1989, 17.. 409 - 413.
  • 7Falcone T, Bedaiwy MA. Fertility preservation and pregnancy outcome after malignancy. Curr Opin Obstet Gynecol, 2005, 17: 21-26.
  • 8Minton SE, Munster PN. Chemotherapy- induced amenorrhea and fertility in women undergoing adjuvant treatment for breast cancer. Cancer Control, 2002, 9: 466 - 472.
  • 9Goldhirsch A, Gelber RD, Castiglione M. The magnitude of endocrine effects of adjuvant chemotherapy for premenopausal breast cancer patients. The International Breast Cancer Study Group. AnnOncol, 1990, 1: 183-188.
  • 10Nasiry J, Walton C, Lindow SW, et al. Spontaneous recover- y of chemotherapy- induced primary ovarian failure: implica- tions for management. Clin Endocrinol, 1997, 46:217 -219.

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