期刊文献+

炎症及神经内分泌相关标志物与脑梗死预后 被引量:2

原文传递
导出
摘要 脑卒中是世界第三大致死疾病,也是引起长期残疾的主要疾病之一。绝大多数卒中(87%)为缺血性卒中[1]。判断脑梗死预后是神经科医生重要的任务之一,也是患者及亲属最关心的问题之一,脑梗死预后的血清学标志物可快速检测,它可作为脑梗死危险分层、监控疾病和治疗反应、研发神经保护治疗靶点和治疗试验重要依据。笔者针对脑梗死的两个发病机制:炎症及神经内分泌相关血清学标志物对脑梗死预后判断进展作一个综述。
作者 徐守权
出处 《中国基层医药》 CAS 2015年第11期1746-1749,共4页 Chinese Journal of Primary Medicine and Pharmacy
  • 相关文献

参考文献36

  • 1Lloyd-Jones D, Adams R J, Brown TM, et al. Heart Disease and Stroke Statistics-2010 Update: a report from the American Heart Association[ J ]. Circulation ,2010,121 (7) : e46-e215.
  • 2Whiteley W,Tian Y,Jickling GC. Blood biomarkers in stroke:re- search and clinical practice [ J 1. Int J Stroke, 2012,7 ( 5 ) : 435- 439.
  • 3Emsley HC, Smith C J, Georgiou RF, et al. A randomised Phase II study of interleukin-1 receptor antagonist in acute stroke patients [ J ]. J Neurol Neurosurg Psychiatry,2005,76 (10) : 1366-! 372.
  • 4Protopsaltis J, Kokkoris S, Korantzopoulos P, et al. Prediction of long-term functional outcome in patients with acute ischcmic non- embolic stroke[ J]. Atherosclerosis,2009,203 ( 1 ) :228-235.
  • 5Castillo J, Alvarez-Sabin J, Martinez-ila E, et al. Inflammation markers and prediction of post-stroke vascular disease recurrence : the MITICO study[J]. J Nem-ol,2009,256(2) :217-224.
  • 6Whiteley W, Jackson C, Lewis S, et al. Association of circulating inflammatory markers with recurrent vascular events after stroke. A prospective cohort study [ J ]. Stroke,2011,42 (1) :10-16.
  • 7Welsh P, Lowe G, Chalmers J, et al. Associations of proinflamma- tory cytokines with the risk of recurrent stroke [ J ]. Stroke,2008, 39(8) :2226-2230.
  • 8Murakami Y, Saito K, Hara A, et al. Increases in tumor necrosis factor-a following transient global cerebral ischemia do not con- tribute to neuron death in mouse hippocampus[ J]. J Neurocbem, 2005,93(6) :1616-1622.
  • 9Rosell A, Alvarez-Sabin J, Arenillas JF, et al. A matrix metallo- protcinase protein array reveals a strong relation between MMP-9 and MMP-13 with diffusion-weighted image lesion increase in hu- man stroke[ J]. Stroke ,2005,36 (7) : 1415-1420.
  • 10Licata G, Tuttolomondo A, Di Raimondo D, et al. Immuno-inflam- matory ativation in acute cardio-embolic strokes in comparison with other subtypes of ischaemic stroke [ J ]. Thromb Haemost, 2009,101 (5) :929-937.

同被引文献17

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部