摘要
糖尿病与结肠癌的关系被越来越多的研究所证实。糖尿病患者容易引起结肠癌,且其治疗效果和预后比单纯结肠癌差。为了预防和治疗糖尿病合并结肠癌,很多研究关注糖尿病与结肠癌的关系。一些研究认为,胰岛素及胰岛素样生长因子1、晚期糖基化产物受体及其配体是重要的机制。在细胞、动物、人体标本的研究中,越来越多的证据支持这些因素与糖尿病及结肠癌的关联有关。该文就糖尿病与结肠癌关系的研究进展予以综述。
More and more researches have proved the relationship between diabetes and colon cancer. Diabetics are more prone to develop colon cancer,and simple colon cancer has a better therapeutic effect and prognosis than the colon cancer with diabetes. For the prevention and treatment of colon cancer, many reports are focused on how diabetes mellitus affect colon cancer, and some reports believe insulin and insulin like factor-1 ,advanced glycosylation product receptor and its ligand are important mechanisms. In the study of cells, animal and human specimens, more and more evidences support the association between diabetes and colon cancer, and here is to make a review of the research progress.
出处
《医学综述》
2015年第10期1783-1785,共3页
Medical Recapitulate
基金
广西自然科学基金(2010GXNSFA013132)
关键词
糖尿病
结肠癌
胰岛素样生长因子
晚期糖基化产物受体
Diabetes mellitus
Colorectal cancer
Insulin-like growth factor
Receptor for advanced glycation end products
