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重视ICU患者噬血细胞综合征的诊断和治疗 被引量:4

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摘要 噬血细胞综合征(hemophagocytic syndrome,HPS)又称噬血细胞性淋巴组织细胞增生症(hemophagocytic lymphohistiocytosis,HLH),自1952年首次报道以来,因临床表现多样、病程发展迅猛、病死率高而受到重视.HLH不是一种独立的疾病,是各种致病因素如遗传、免疫抑制剂、恶性肿瘤、感染等导致机体免疫功能紊乱引起的一种过度炎性反应,依照病因HLH分为原发性和继发性.
出处 《内科急危重症杂志》 2015年第2期86-88,共3页 Journal of Critical Care In Internal Medicine
作者简介 通信作者:李树生,E-mail:shushengli16@sina.com
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参考文献22

  • 1Larroche C. Hemophagocytic lymphohistiocytosis in adults: diagnosis and treatment[ J]. Joint Bone Spine,2012,79(4) :356-361.
  • 2Vincent FB, Mehul KS, Julie T, et al. Association of Crohn disease, dhiopurines, and drimary Epstein-Barr Virus Infection with Hemoph- agocytic dymphohistiocytosis [ J ]. J Pediatr, 2011,159 ( 5 ) : 808 -812.
  • 3Tsuji T,Hirano T,Yamasaki H,et al. A high sIL-2R/ferritin ratio is a useful marker for the diagnosis of lymphoma-associated hemophagocyt- ic syndrome [ J ]. Ann Hemato1,2014,93 (5) :821-826.
  • 4Athreya BH. Is macrophage activation syndrome a new entity [ J ] ? Clin Exp Rheumatol,2002,20(2) :121-123.
  • 5黄文秋,王旖旎,王昭.噬血细胞性淋巴组织细胞增生症的治疗进展[J].临床荟萃,2014,29(10):1147-1150. 被引量:3
  • 6Rajagopala S, Singh N, Agarwal R, et al. Severe hemophagocytic lym- phohistiocytosis in adults experience from an intensive care unit from North India [ J ]. Indian .l of Crit Care Med ,2012,19 (4) : 198-203.
  • 7Buyse S, Teixeira L, Galicier L, et al. Critical care management of pa- tients with hemophagocytic lymphohistiocytosis [ J ]. Intensive Care Med,2010,36 ( 1 ) : 1695-1702.
  • 8Tateishi Y, Oda S, Sadahiro T, et al. Continuous hemodiafiltration in the treatment of reactive hemophagocytic syndrome refractory to medi- cal therapy[ J]. Trans and Aphere Sci,2009.40( 1 ) ..33-40.
  • 9Stepp SE, Dufoureq Lagelouse R, Le Deist F, et al. Perforin gene de- fects in familial hemophagocytic lymphohistiocytosis [ J ]. Science, 1999,286 (5446) : 1957-1959.
  • 10eldmann J,Callebant I,Raposo G,et al. Munc 13-4 is essential for cy- tolytic granules fusion and is mutated in a form of familial hemophago- cytic lymphohistiocytosis ( FHL3 ) [ J ]. Cell ,2003,115 (4) :461 473.

二级参考文献41

  • 1孔晋星,付荣明,周凤珍.嗜血细胞综合征细胞形态学诊断分析[J].现代检验医学杂志,2005,20(1):75-76. 被引量:8
  • 2Janka G. Hemophagocytic lymphohistiocytosis:when the immune sys- tem runs amok [ J ]. Klin Padiatr, 2009,221 ( 5 ) : 278-285.
  • 3Gholam C, Grigoriadou S, Gilmour KC, et al. Familial haemophagoeyt- ic lymphohistioeytosis: advances in the genetic basis, diagnosis and management [ J ]. Clin Exp Immuno1,2011,163 ( 3 ) :271-283.
  • 4Janka G E. Familial and Acquired Hemophagocytic Lymphohistiocyto- sis[J]. Annu Rev Med,2012,63:233-246.
  • 5Szyper-ga'avitz M. The hemophage syndrome / macrophage activation syndrome:a final common pathway of a cytokine storm [ J]. Isr Med Assoc ,2009,11 ( 10 ) :633-634.
  • 6Mahlaoui N, Ouachee-Chardin M, de Saint Basile G, et al. Immuno- therapy of familial hem@agocytic lymphohistiocytosis with antithy- moctye globulins: a single-center retrospective report of 38 patients [ J ]. Pediatrics,2007,120 ( 3 ) : e622-628.
  • 7Hu Y, Xu J, Wang L, et al. Treatment of haemophagocytic lymphohis- tiocytosis with cyclophosphamide, vincristine, and prednisone [ J ]. Swiss Med Wkly,2012,142 :w13512.
  • 8Takahashi N, Chubachi A, Kume M, et al. A clinical analysis of 52 a- dult patients with hemophagocytic syndrome: the prognostic signifi- cance of the underlying diseases [ J ]. Int J Hematol, 2001,74 ( 2 ) : 209-213.
  • 9Janka GE,Schneider EM.Modem management of children with haemophagocytic lymphohistiocytosis[J].Br J Haematol,2004,124(1):4-14.
  • 10Janka GE,Lehmberg K.Hemophagocytic lymphohistiocytosis:pathogenesis and treatment[J].Hematology Am Soc Hematol Educ Program,2013,2013:605-611.

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