摘要
【目的】探讨2型糖尿病早期肾损害患者中医证素分布规律。【方法】选取200例2型糖尿病早期肾损害患者,采用证素辨证方法分析2型糖尿病早期肾损害患者中医病位、病性证素分布规律特点。【结果】(1)中医病位:肾的证素积分最高,其次为脾和经络;肾、脾、经络的证素积分与肝、心、肺、胃比较,差异均有统计学意义(P<0.01)。(2)中医病性:实性证素主要为痰、血瘀、湿,其比率为痰>血瘀>湿。虚性证素主要为阴虚、气虚和阳虚,其比率为阴虚>气虚>阳虚。(3)证素分布:肾病中阴虚证素积分最高,脾病中气虚证素积分最高,经络证素中血瘀积分最高。【结论】肾、脾、经络是2型糖尿病早期肾损害的主要病位;本病虚证以阴虚、气虚和阳虚偏重,实证以痰、血瘀、湿偏重;临床多见肾阴虚证、脾气虚证及瘀血阻络证等证型。
Objective To explore the regularity of the distribution of traditional Chinese medical syndrome elements in early renal injury patients with type 2 diabetes mellitus （ T2DM） . Methods A total of 200 patients with T2DM early renal injury were enrolled into the study. Syndrome element differentiation was carried out for the analysis of the distribution of syndrome location and syndrome nature. Results （ 1） Kidney had the highest scores of syndrome location , and then came the spleen, and meridians and collaterals . The syndrome location scores of kidney, spleen, meridians and collaterals differed from those of liver, heart, lung, and stomach （ P〈0.01） . （ 2） In excess syndrome elements, the percentage of syndrome elements of phlegm, blood stasis, dampness was in decreasing sequence. In deficiency syndrome elements, the percentage of syndrome elements of yin deficiency, qi deficiency, and yang deficiency was in decreasing sequence. （ 3） For the distribution of syndrome elements, kidney yin deficiency had the highest scores, next came spleen qi deficiency, and finally came blood stasis of meridians and collaterals. Conclusion In T2DM early renal injury patients, kidney, spleen, meridians and collaterals are the main affected location; yin deficiency, qi deficiency, and yang deficiency are the predominant deficiency syndrome elements, and phlegm, blood stasis, dampness are the predominant excess syndrome elements. Kidney yin deficiency, spleen qi deficiency , and blood stasis of meridians and collaterals are the commonly-seen syndrome patterns in T2DM patients with early renal injury.
出处
《广州中医药大学学报》
CAS
2015年第3期406-409,414,共5页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
广西名老中医民族医传承工作室建设项目(编号:桂卫中[2014]9号)
关键词
2型糖尿病
早期肾损害
中医证候
证素
Type 2 diabetes mellitus
Early renal injury
Traditional Chinese medical syndrome
Syndrome elements
作者简介
张望之（1986-），女，主治医师；E-mail：339461539@qq．com
通讯作者：李双蕾，女，主任医师，教授；E-mail：lslei66@126．com
