摘要
骨质疏松症(osteoporosis,OP)是以骨量减少、骨的微观结构退化为特征的一种全身性骨骼疾病,是一种常见病、多发病,是一个世界范围的健康问题,其致死率与乳腺癌相当。据调查,仅2006年中国就有9060万人患骨质疏松症,占我国总人口的7.01%,男女比例1∶6。随着老龄化加快,如何防治骨质疏松症成为人们关注的焦点。因此,寻求一种可最大程度贴合人体实际,模拟本病临床症状和病理变化对于防治骨质疏松症具有重要意义。作为该病前期的研究内容,动物实验的研究值得我们去深入挖掘。大鼠是目前造模使用最广泛的一种实验动物,现就近15年来大鼠用于骨质疏松症大鼠的造模方法研究进展进行简述。
Osteoporosis （ osteoporosis, OP ） is degraded to osteopenia, bone microstructure was characterized by a systemic skeletal disease, is a common disease, is a health issue worldwide, the death rate of breast cancer and quite.According to the survey, in 2006 Chinese 90 600 000 had osteoporosis, accounting for 7.01% of the total population, the proportion of men and women 1 to 6, in which the female incidence rate is high.With the accelerated aging, how to prevent and cure osteoporosis has become the focus of attention..Therefore, how to simulate the clinical symptoms and pathological changes of this disease, is of great significance for the prevention and treatment of osteoporosis drug research and development.As the research content of the preliminary of the disease, research progress of animal experiment is worth in-depth mining, while the rat is now used for an experimental animal model most widely.The past 15 years for OP rats made progress mode method is introduced.
出处
《辽宁中医药大学学报》
CAS
2015年第5期248-251,共4页
Journal of Liaoning University of Traditional Chinese Medicine
作者简介
卢锦东（1992-），男，广东潮州人，本科学生，研究方向：中医内科学。
