摘要
子宫肌瘤(Uterine Leiomyoma,UL)是育龄期妇女生殖器官中最常见的良性肿瘤之一,主要由平滑肌纤维及结缔组织组成。但由于与发病相关的因素众多而且复杂,迄今为止,其病理机制尚未完全明确。中医认为其发生发展与气、痰、湿、瘀等因素的长期刺激密切相关,导致气滞、痰湿、血瘀停积于胞宫而成;现代医学研究认为子宫肌瘤发生可能与性激素及其受体、细胞增殖与凋亡、信号转导途径异常、分子遗传学等方面有关,从中医及西医学两个方面对子宫肌瘤相关研究进展作一综述。
Uterine leiomyoma is one of the most common benign tumors that occurs in female reproductive organs of childbearing age which mainly composed of smooth muscle fibers and connective tissue. But its pathogenesis is not com- pletely clear so far because of the complete and numerous factors. TCM believes that its development is closely related to long -term stimulation that contain the sputum, wet, stasis and other factors. Modern medine researches suggests that u- terine leiomyoma may associated with sex hormones and their receptors, cell proliferation and apoptosis, signal transduc- tion pathway abnormalities, molecular genetics and so on. This article make a summary about the research progress of U- terine Leiomyoma from two aspects of traditional Chinese medicine and Western medicine.
出处
《中华中医药学刊》
CAS
北大核心
2015年第5期1110-1112,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金项目(81001668)
四川省科学技术厅项目(2015JY0215)
四川省人力资源和社会保障厅项目(003099013002)
四川省中医药管理局项目(2014K073)
成都市科技局计划项目(12DXYB297JH-002)
关键词
子宫肌瘤
发病机制
综述
Uterine Leiomyoma
Pathogenesis
Summary
作者简介
沈东成(1989-),女,重庆人,硕士研究生,研究方向:实验方剂学科研、药理毒理等研究。
通讯作者:余成浩(1976-),男,重庆人,教授,博士,研究方向:实验方剂学教学科研、药理毒理等新药开发研究。E.mail:yuholy@126.com。