摘要
目的：根据《抗菌药物临床应用指导原则》加强管理后，探讨骨科围手术期抗菌药物使用情况。方法：对2011年3月-2011年12月骨科无菌手术患者793例，2012年3月-2011年12月骨科无菌手术患者857例，预防性使用抗菌药物进行比较评价。结果：2011、2012年组围手术期抗菌药物使用率为100％、52．6％，使用时间为（8．61±4．47）d、（2．11±1．34）d，两组差异有统计学意义（P〈0．05）。2011组切口感染率为0．56％，2012组切口感染率为0．42％。结论：强化管理后，短时间、规范、合理使用抗菌药物安全、有效，能显著减少围手术期抗菌药物的使用率，不增加切口感染的发生率。
Objective To discussion the clinical application of antibiotics in the peroperative period after guided by ＂Guiding Principles of Clinical application of antibacterial drug＂. Method The data of 793 Aseptic operation patients in department of Orthopedics from March to December 2011 and 857 Aseptic operation patients from March to December 2012 were selected retrospectively to compare and review the anti- biotics utilization the situation of perioperative period. Results The percentage of antibiotics use in 2011 group and 2012 group were 100% and 52. 6% retrospectively（P 〈0. 05）. The use of time were （8. 61±4. 47） d and （2. 11± 1.34） d in two group retrospectively,the differ- ence was statistically significant （ P 〈 0. 05 ）. The rate of incision infection were 0. 56% and 0. 42% retrospectively. Condusion The study shows that the method of short time, norms and rational use of antibiotics is safe and effective after strengthening antibiotics management, which can significantly reduce antibiotic use and does not increase the occurrence of incision infection.
出处
《吉林医学》
CAS
2015年第10期1973-1975,共3页
Jilin Medical Journal
关键词
骨科
围手术期
抗菌药物
Orthopedics
Perioperative period
Antibacterials
