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髋、膝关节置换术抗纤溶药序贯抗凝血药平衡 被引量:9

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摘要 髋、膝关节置换术(total hip arthroplasty,THA;total knee arthroplasty,TKA)常伴随大量失血及高输血率,文献报道THA、TKA围手术期总失血量多在1000 ml以上,输血率为30%-60%。大量失血会增加手术风险,输血也会增加免疫反应、疾病传播的风险,同时加重患者的经济负担[2]。氨甲环酸(tranexamic acid,TXA)是一种纤溶酶抑制剂,可有效减少THA、TKA围手术期的失血量、降低输血率,
作者 裴福兴
出处 《中国骨与关节外科》 2015年第1期7-10,共4页 Chinese Journal of Bone and Joint Surgery
基金 国家卫计委2013年度卫生行业科研专项(2013020007)
作者简介 通信作者:裴福兴,E-mail:peifuxing@vip.163.com
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