摘要
胃肠间质瘤(gastrointestinal stromal tumors,GIST)是胃肠道一种相对罕见的肿瘤,占消化道间叶性肿瘤的大部分,起源于胃肠道固有肌层和黏膜肌层,可发生在消化道的任何部位。由于其对放化疗均不敏感,因此,对于局限性的GIST的首选治疗方式仍为外科手术切除。近年来,随着消化内镜诊疗技术不断发展和成熟,以内镜黏膜下剥离术(ESD)为基础的内镜切除术也逐渐应用于GIST的治疗中,而且因其具有创伤小、疗效确切、恢复快、病人术后生活质量高等优点正日益被接受并推广。
Gastrointestinal stromal tumor （GIST）, a kind of relatively rare gastrointestinal tumor, is the most common mesenchymal tumors of the gastrointestinal tract. GIST originated from gastrointestinal muscularis propria and muscularis mucosae and can occur in any part of the digestive tract. GIST is not sensitive to radiotherapy or chemotherapy and complete surgical resection of GIST is considered to have curative effect. However, in recent years, endoscopic resection is increasingly accepted and has been applied to treat the local GIST without lymph node metastasis, owning to the techniques of endoscopic resection is safer, more effective, faster recovery with satisfactory surgical outcome.
出处
《中国实用外科杂志》
CSCD
北大核心
2015年第4期378-382,共5页
Chinese Journal of Practical Surgery
基金
上海市科委重大课题(No.11411950500
No.11411950501
No.13411951600)
国家自然科学基金项目(No.81101566)
上海市卫生局人才基金(No.XYQ2011017)
上海市科委启明星计划(No.12QA1400600)
上海市卫计委适宜技术推广项目(No.2013SY045
No.2013SY054)
上海市人才基金(No.201305)
教育部博士点基金(No.20120071110061)
关键词
胃肠间质瘤
内镜切除术
内镜黏膜下剥离术
gastrointestinal stromal tumor
endoscopic resection
endoscopic submucosal dissection
作者简介
通信作者：钟芸诗，E-mail：zhongamy2002@126．com
