摘要
淋巴结转移是影响胃癌患者预后的重要因素，准确的淋巴结转移状态评估可以促进个体化的手术实施及预后。放射免疫技术可用于胃癌及转移淋巴结示踪，但研究中尚存在很多有待解决的问题和局限。然而随着单克隆抗体、基因工程抗体及核素分子功能显像等技术的不断发展，这一技术有望同时实现肿瘤靶向、术前显像和术中实时示踪的功能，以进行更准确的肿瘤分期，采取最佳的治疗方案。本文对放射免疫技术在胃癌及转移性淋巴结示踪中的应用现状及前景做一综述。
Lymph node metastasis is one of the factors associated with the prognosis of gastric cancer patients. While precise evaluation of nodal status can promote the personalized surgery and improve prognosis. Although with many unsolved problems and limitations, radioimmune technique can be used to trace gastric cancer and metastatic lymph nodes. With the constant development of monoclonal antibody , genetic engineering antibody, nuclide molecular functional imaging, the radioimmune technique may allow tumor targeting , preoperative imaging, and intraoperative tracing. Therefore, more accurate tumor staging and optimal therapeutic regimen may be possible. This review mainly focuses on the utility of radioimmuno-tracing technique in metastatic lymph node for gastric cancer.
出处
《中华胃肠外科杂志》
CAS
CSCD
北大核心
2015年第3期298-300,共3页
Chinese Journal of Gastrointestinal Surgery
基金
国家自然科学基金（81372364）
关键词
胃癌
淋巴结
放射免疫示踪
Stomach neoplasms
Lymph node
Radioimmuno-tracing
作者简介
通信作者：管文贤，Email：Guan-wx@163．com
