期刊文献+

沙门菌T3SS相关效应蛋白作用机制的研究进展 被引量:4

Research progress on T3SS relative effector protein of Salmonella
在线阅读 下载PDF
导出
摘要 沙门菌是人兽共患病原菌,能感染宿主并导致严重的并发症和死亡。沙门菌的致病性主要是由沙门菌SPI-1和SPI-2编码的T3SS的效应蛋白相互作用的结果。本文主要对T3SS相关效应蛋白在沙门菌感染的不同阶段发挥的功能进行综述,以期为进一步了解沙门菌致病机理提供参考。 Salmonella is a pathogenic bacteria to human and animals ,which can cause seriously complication and death . Salmonella pathogenicity is from the reactions of SP‐1 and SP‐2 T3SS effector proteins .In this paper ,the functions of different T3ss effector proteins in different infection periods is reviewed to provide a reference for further understanding the pathogenesis mechanisms of Salmonella .
出处 《中国人兽共患病学报》 CAS CSCD 北大核心 2015年第3期277-280,288,共5页 Chinese Journal of Zoonoses
基金 国家自然科学基金(31172299 31320103907) 教育部新世纪优秀人才支持计划(NCET-12-0745) 江苏省第九批"六大人才高峰"高层次人才项目(NY-028) 2012年度高校"青蓝工程"中青年学术带头人培养对象项目 江苏省研究生科研创新计划(KYZZ_0368) 江苏省高校优势学科建设工程项目联合资助~~
关键词 沙门菌 T3SS效应蛋白 功能 Salmonella T3SS effector proteins functions
作者简介 通讯作者:潘志明,Email:zmpan@yzu.edu.cn
  • 相关文献

参考文献24

  • 1贺奋义.沙门氏菌的研究进展[J].中国畜牧兽医,2006,33(11):91-95. 被引量:43
  • 2Gradel KO, Nielsen HL, Schonheyder HC, et al. Increased short and long-term risk of inflammatory bowel disease after Salmonella or Campylobacter gastroenteritis[J]. Gastoenterology, 2009, 137(2): 495-501. doi:10.1053/j. gastro.2009.04.001.
  • 3Brawn LC, Hayward RD, Koronakis V. Salmonella SPI1 effector SipA persists after entry and cooperates with a SPI2 effector to regulate phagosome maturation and intracellular replication[J]. Cell Host Microbe,2007,1(1): 63-75. doi:10.106/j.chom.2007.02.001.
  • 4Burkinshaw BJ, Prehna G, Worrall LJ, et al. Structure of Salmonella effector protein SopB N-terminal domain in complex with host Rho GTPase Cdc42[J]. J Biol Chem, 2012, 287(16): 13348-13355. doi:10.1074/jbc.M111.331330.
  • 5Hanisch J, Kolm R, Wozniczka M, et al. Activation of a RhoA myosinII dependent but Arp2/3 complex independent pathway facilitates Salmonella invasion[J]. Cell Host Microbe, 2011, 9(4): 273-285. doi:10.1016/j.chom.2011.03.009.
  • 6Alto NM, Shao F, Lazar CS, et al. Identification of a bacterial type III effector family with G protein mimicry functions[J]. Cell, 2006, 124(1): 133-145. doi:10.1016/j.cell.2005.10.031.
  • 7Huang Z, Sutton SE, Wallenfang AJ, et al. Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics[J]. Nat Struct Mol Biol, 2009, 16(8): 853-860. doi:10.1038/nsmb.1647.
  • 8Choi HW, Brooking DR, Neupane S, et al. Salmonella Typhimurium impedes innate immunity with a mast cell suppressing protein tyrosine phosphatase, SptP[J]. Immunity, 2013, 39(6): 1108-1120. doi:10.1016/j.immuni.2013.11.009.
  • 9Button JE, Galan JE. Regulation of chaperone effector complex synthesis in a bacterial type III secretion system[J].Mol Microbiol, 2011, 81(6): 1474-1483. doi:10.1111/j.1365-2958. 2011. 07784.X.
  • 10Abrahams GL, Muller P, Hensel M. Functional dissection of SseF, a Type III effector protein involved in positioning the Salmonella containing vacuole[J]. Traffic, 2006, 7(8): 950-965. doi:10.1111/j.1600-0854.2006.00454.x.

二级参考文献8

  • 1He S Y.Type Ⅲ protein secretion systems in plant and animal pathogenic bacteria[J].Annu Rev Phytopathol,1998,36:363~392.
  • 2Jepson M A,Clark M A.The role of M cells in Salmonella infection[J].Microbes Infect,2001(3):1183~1190.
  • 3Jones M A,Wigley P,Page K L,et al.Salmonella enterica serovar gallinurum requires the Salmonella pathogenicity island 2 type Ⅲ secretion system but not the Salmonella pathogenicity island 1 type Ⅲ secretion system for virulence in chickens[J].Infection and Immunity,2001,69:5471~5476.
  • 4Macus S L,Brumell J H,Pfeifer C G,et al.Salmonella pathegenicity island:big virulence in small packages[J].Microbes and infection,2000,2:145~156.
  • 5Platt D J,et al.Epidemiology and Infection[A],1987,99:137~142.
  • 6Terakado,Serkizakl,Hashimoto,et al,Correlation between the presenc of a fifty-Megadalton plasmid in Salmonella Dublin and virulence for mice[J].Infection and Immunity,1983,41(1):443~444.
  • 7Willshaw G A,et al.Antimicrobial Chemotherapy[A],1980,6:763~773.
  • 8Tompkingls,et al.Infections Disease[A],1986,154:156~162.

共引文献42

同被引文献22

引证文献4

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部