摘要
目的：分析妊娠期糖尿病（GDM）孕妇外周血糖化血红蛋白（HbA1c）检测水平的临床应用价值。方法：回顾分析我院2012年4月～2013年12月在本院妇产科门诊和住院分娩建卡的GDM组孕妇86例和正常组孕妇106例进行外周血HbA1c水平检测、空腹血糖（FPG）监测和口服糖耐量实验（OGTT），并对检测结果进行比较统计学分析。结果：GDM组HbA1c、FPG、OGTT检测水平以及HbA1c、FPG和 OGTT的阳性检出率均明显高于正常组，（P＜0.05），HbA1c、FPG和 OGTT的阳性检出率分别为89.5%、45.3%、59.3%。结论：HbA1c水平检测可作为GDM诊断、治疗、筛查及其预后评估的主要指标之一，有利于提高GDM的阳性检出率以及降低母婴并发症发生率，可作为GDM的GLU水平监测有效手段。
Objective：To analyze the clinical application values of glycosylated hemoglobin（HbA1c）testing for peripheral blood of gestational diabetes mellitus（GDM）pregnant women. Methods：Reviewed the outpatient and hospitalized pregnant women from April 2012 to December 2013 in gynecology and obstetrics department of our hospital. We divided them into two groups： the GDM group including 86 cases and the normal group including 106 cases. The levels of HbA1c in peripheral blood, fasting blood glucose（FPG） experimental monitoring and oral glucose tolerance（OGTT） were compared in the two group, and the results were statistically analyzed.Results：In GDM group, HbA1c,FPG,OGTT levels and the positive rates of HbA1c, FPG ,OGTT were significantly higher than that of normal group,（P〈0.05）,with the positive rates of HbA1c,FPG and OGTT were 89.5%,45.3%,59.3% respectively. Conclusions：The HbA1c test can be one of the main indicators to evaluate GDM in the diagnosis, treatment, screening and prognosis, which is benefit for enhancing the positive rate of GDM and reducing the incidence of the complications for mothers and infants, also can be used as the effective mean of monitoring the levels of GLU for GDM cases.
出处
《医学检验与临床》
2015年第1期13-15,共3页
Medical Laboratory Science and Clinics
关键词
妊娠期糖尿病
糖化血红蛋白
口服糖耐量实验
外周血
Gestational diabetes meUitus
Glycated hemoglobin A1C
Oral glucose tolerance test
Peripheral blood
