期刊文献+

院前急救对食管胃静脉曲张大出血患者近期预后的影响 被引量:3

Effect of pre-hospital care on short-term prognosis of patients with esophageal and gastric variceal bleeding
在线阅读 下载PDF
导出
摘要 目的探讨院前急救对食管胃静脉曲张大出血(esophageal and gastric variceal bleeding,EGVB)患者近期预后的影响。方法回顾性分析秦皇岛市第一医院2011年1月-2013年12月收治的EGVB患者174例,按就诊方式分为院前急救组(观察组)和自行来院组(对照组)。观察组86例:经院前止血、补液等现场急救后,转运入院;对照组88例:未经院前急救,自行或家属护送入院。两组入院后后续用药及治疗均相同,比较两组临床疗效、并发症情况。结果观察组与对照组自救反应时间、平均止血时间相比,差异无统计学意义(P>0.05);观察组第一处置时间、输血量、住院天数均少于对照组,差异有统计学意义(P<0.01);观察组死亡率13.9%,对照组15.9%,两组比较,差异无统计学意义(P>0.05),但观察组肝性脑病、肝肾综合征、感染等并发症发生率(25.6%)明显低于对照组(39.8%),差异有统计学意义(P<0.05)。结论对EGVB患者实施迅速有效的院前急救,能提高临床疗效,减少并发症,改善患者近期预后。 Objective To investigate the effect of pre-hospital care on short-term prognosis of patients with esophageal and gastric variceal bleeding( EGVB). Methods Clinical data of 174 patients with EGVB were collected and retrospectively analyzed from Jan. 2011 to Dec. 2013. All patients were divided into the pre-hospital care group( the observation group) and the self-going group( the control group) according to way of admission to hospital. Eighty-six patients in the observation group received pre-hospital care,including hemostasis,fluid resuscitation and other field first aid before transferring to hospital. Eighty-eight patients in the control group had no treatment before themselves went or relatives escorted them to hospital. Two groups were treated with the same medication and treatment after entering the hospital and then the clinical efficacy and complications were compared. Results There was no significant difference in selfaid reaction time and the average time of hemostasis between two groups( P 〉0. 05). The first disposal time,amount of blood transfusion and hospital stay of the observation group were significantly less than those of the control group( P〈 0. 01). No significant difference in mortality was found between two groups(13. 9% vs 15. 9%,P 〉0. 05),but the total incidence of hepatic encephalopathy,hepatorenal syndrome and infection was significantly lower in the observation group than in the control group(25. 6% vs 39. 8%,P〈 0. 05). Conclusion Rapid and effective pre-hospital first aid for patients with EGVB can improve the clinical efficacy,reduce complications,thus improve the short-term prognosis of patients.
出处 《胃肠病学和肝病学杂志》 CAS 2015年第2期201-203,共3页 Chinese Journal of Gastroenterology and Hepatology
关键词 院前急救 食管胃静脉曲张出血 近期预后 并发症 Pre-hospital care Esophageal and gastric variceal bleeding Short-term prognosis Complication
作者简介 程瑶,研究方向:院前急危重症的诊断和治疗。E-mail:hexing4882@sina.com 通讯作者:纪桂贤,硕士研究生,副主任医师,研究方向:消化道疾病的诊疗及内镜下治疗。E—mail:jgx2001@eyou.com
  • 相关文献

参考文献7

  • 1卢向东,张志广.食管胃静脉曲张出血的治疗进展[J].医学综述,2011,17(3):403-405. 被引量:6
  • 2Pateron D. Gastrointestinal hemorrhage. Evaluation and non specific treatment [ J ]. Gastroenterol Clin Biol, 2004, 28 Spec No 2: B179-B185.
  • 3王志峰.院前急救在医学中的作用[J].中国误诊学杂志,2011,11(16):3781-3783. 被引量:2
  • 4Thuresson M, Jarltiv MB, Lindahl B, et al. Thoughts, actions, and factors associated with prehospital delay in patients with acute coronary syndrome [J]. Heart Lung, 2007, 36(6) : 398-409.
  • 5李兆申,湛先保.食管胃静脉曲张出血的诊治建议(草案)[J].中华内科杂志,2006,45(6):524-526. 被引量:46
  • 6Schiff ER,Sorrell MF,Maddrey WC.希夫肝脏病学[M].黄志强译.9版.北京:化学工业出版社,2006:419-424.
  • 7de Franehis R, Baveno V Faculty. Revising consensus in portal hyper- tension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension [ J]. J Hepatol, 2010, 53 (4) : 762-768.

二级参考文献34

  • 1陆星华,张泰昌.食管胃静脉曲张内镜下诊断和治疗规范试行方案(2003年)[J].中华消化内镜杂志,2004,21(3):149-151. 被引量:433
  • 2张筱虹,李青.我国10年院前急救医学文献计量分析[J].中国急救医学,1996,16(1). 被引量:22
  • 3王一镗.加紧实施中国心肺复苏术普及培训工程[J].中国急救医学,1993,13(5).
  • 4Moodley J,Lopez R,Carey W.Compliance with practice guidelines and risk of a first esophageal variceal hemorrhage in patients with cirrhosis[J].Clin Gastroenterol Hepatol,2010,8(8):703-708.
  • 5Groszmann RJ,Garcia-Tsao G,Bosch J,et al.Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis[J].N Engl J Med,2005,353(21):2254-2261.
  • 6Merkel C,Marin R,Angeli P,et al.A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis[J].Gastroenterology,2004,127(2):476-484.
  • 7Gluud LL,Klingenberg S,Nikolova D,et al.Banding ligation versus beta blockers as primary prophylaxis in esophageal varices:systematic review of randomized trials[J].Am J Gastroenterol,2007,102(12):2842-2849.
  • 8Loren L.Primary prophylaxis of esophageal variceal bleeding:an endoscopic approach[J].Hepatology,2010,52(6):944-945.
  • 9Lo GH,Chen WC,Wang HM,et al.Controlled trial of ligation plus nadolol versus nadolol alone for the prevention of first variceal bleeding[J].Hepatology,2010,52(1):230-237.
  • 10Garcia-Tsao G,Bosch J.Management of varices and variceal hemorrhage in cirrhosis[J].N Engl J Med,2010,362(9):823-832.

共引文献52

同被引文献26

引证文献3

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部