摘要
目的综述生物敷料的研究进展。方法查阅国内外相关文献,从生物敷料概况以及各类型生物敷料研究进展方面进行分析总结。结果与传统敷料相比,生物敷料可更好地促进伤口愈合。生物敷料主要分为天然材料类、人工合成材料类和载药类敷料,其中天然材料类敷料以海藻酸盐敷料为主,该类敷料促进伤口愈合已获大量研究证实;人工合成材料类敷料包括薄膜类、液体类、水胶体类、水凝胶类及泡沫类,各具优缺点,可根据需要选用;载药类敷料可发挥负载药物的作用,进一步促进伤口愈合,采用微囊技术构建敷料以及选择中药作为负载药物是其研究方向。结论目前研究的生物敷料类型较多,其临床应用前景广泛,但各有优缺点,有待进一步研究完善其功效。
Objective To review the research progress of modern biological dressings. Methods The related literature at home and abroad was reviewed, analyzed, and summarized in the progress of biological dressing situation and various types of biological dressing research. Results Compared with the traditional dressing, the biological dressing can greatly promote wound healing. Biological dressings are mainly divided into the natural materials, artificial synthetic materials, and drug loaded dressings. The natural material dressings are mainly the alginate dressing, this kind of dressing can promote wound healing, which has been confirmed by a large number of studies. The artificial synthetic materials include film dressings, liquid, water colloids, gels, and foam, each has its own advantages and disadvantages, which can be chosen according to need. The drug dressing can play the role of drug loading, and further promote the wound healing; using microcapsule technology to construct the dressing and choosing Chinese medicine as drugs is the research direction of load. Conclusion The experiment and clinical application of biological dressing are many types, clinical application prospect is wide, but each has its own advantages and disadvantages, further study is needed to improve its efficacy.
出处
《中国修复重建外科杂志》
CAS
CSCD
北大核心
2015年第2期254-259,共6页
Chinese Journal of Reparative and Reconstructive Surgery
关键词
生物敷料
藻酸盐
壳聚糖
伤口愈合
Biological dressing
Alginate
Chitosan
Wound healing
作者简介
通信作者：罗波，主治医师，研究方向：泌尿外科学，E-mail：135gongying@163．com
