摘要
目的探讨不同形式位移经校正后对MRS结果可重复性的影响。方法纳入20名被试者于无位移、平动位移、平动-转动位移时分别进行MRS扫描,每次间隔10min,位移状态扫描前由SPM软件自动获取VOI位置,测量并比较平动位移、平动-转动位移经校正后VOI内N-乙酰天门冬氨酸(NAA)、肌酸(Cr)、磷酸肌酸(PCr)和胆碱复合物(Cho)含量及NAA/(Cr+PCr)和Cho/(Cr+PCr);计算上述参数位移对比无位移时差异性系数(CV)和重复性指数(RI)。结果平动位移经校正后各参数与无位移间差异均无统计学意义(P均>0.05),平动-转动位移经校正后除Cr外,NAA、Cho、NAA/Cr+PCr、Cho/Cr+PCr与无位移间差异均有统计学意义(P均<0.01)。平动位移和平动-转动位移经校正后与无位移时比较,NAA、Cho、Cr含量及NAA/(Cr+PCr)、Cho/(Cr+PCr)的平均CV均<12%,重复性可接受;RI值除Cr外,余参数均<20%,重复性可接受。结论 MRS中对患者头部平动位移可准确校正,所得结果重复性较好。
Objective To determine the effect of different displacement on reproducibility of MRS scanning results.Methods Twenty healthy volunteers were enrolled and underwent MRS scanning under non-displacement,translation displacement and translation-rotation displacement,respectively,given a ten-minute rest between each two examinations.The VOI before displacement was corrected by automatic repositioning method using software SPM.The N-acetyl aspartate（NAA）,creatine（Cr）,phosphocreatine（PCr）,choline-containing compounds（Cho）,and NAA/（Cr＋PCr）and Cho/（Cr＋PCr）were measured and compared among each way of displacement.The variance coefficient（CV）and the repeatability index（RI）of each parameter for each displacement compared to non-displacement were calculated.Results No significant differences of above parameters were showed between adjusted translation displacement and non-displacement group（all P〉0.05）,while significant differences of NAA,Cho,NAA/（Cr＋PCr）,Cho/（Cr＋PCr）were found between adjusted translation-rotation displacement and non-displacement group（all P〈0.01）,but not Cr.The CV of above metabolites and ratio between adjusted displacement and non-displacement were all〈12%,meaning acceptable repeatability.The RI of above metabolites and ratio between adjusted displacement and non-displacement were all〈20% excluding Cr,also meaning acceptable repeatability.Conclusion In MRS,translation of subject＇s head position can be accurately adjusted with good repeatable results.
出处
《中国医学影像技术》
CSCD
北大核心
2015年第1期132-136,共5页
Chinese Journal of Medical Imaging Technology
关键词
磁共振波谱学
头部
可重复性结果
位移
Magnetic resonance spectroscopy
Head
Reproducibility of results
Translocation
作者简介
[第一作者]张敏（1987-），女，山东聊城人，硕士，技师。研究方向：磁共振波谱技术与应用。E—mail：zxcvbnm3856@163．com
[通信作者]王培军，同济大学附属同济医院医学影像科，200065。E-mail：tongjipjwang@vip．sina．com
