摘要
目的：分析并观察慢性阻塞行肺疾病（COPD）气肿表型加重期的临床特征。方法：选取2012年7月-2013年4月本院呼吸科收治的COPD患者98例,进行相应HRCT检查,根据HRCT检查结果并结合肺气肿视觉评分法将患者分为两组,其中评分0-8分为无肺气肿组,8~24分为肺气肿组。收集两组患者的临床资料并进行分析和比较。结果：两组在年龄、动脉血氧分压（Pa O2）以及1 s用力呼气容积（FEV1）占预计值%百分比方面比较差异无统计学意义（P〉0.05）;两组在年龄、体质量、动脉血二氧化碳分压（Pa CO2）以及1 s用力呼气容积（FEV1）/用力肺活量（FVC）方面比较差异均有统计学意义（P〈0.05）。结论：肺气肿可反映COPD患者疾病的严重程度,也能为COPD的治疗提供依据。
Objective：To analyze and observe patients with chronic obstructive pulmonary disease（COPD） exacerbation of emphysema phenotype of clinical features.Method：98 COPD patients were selected from July 2012 to April 2013, and check corresponding HRCT, visual grading method based on HRCT findings and combined with emphysema（or references） the patients were divided into two groups, one score in patients within 0-8 points were divided into a group, as a group without emphysema, scores in patients within 8-24 points are divided into a group, a set of emphysema. the clinical data of two groups of patients were collected and analyzed and compared.Result： Two groups of patients in the gender composition, arterial blood oxygen partial pressure（Pa O2） and forced expiratory volume in 1 second（FEV1） expected % percentage had no significant difference（P〉0.05）. Two groups of patients for age, body mass, arterial blood CO2 partial pressure（Pa CO2） and forced expiratory volume in 1 second（FEV1）/forced vital capacity（FVC） had significant differences（P〉0.05）.Conclusion：COPD patients with emphysema may reflect the severity of the disease, also provide the basis for the treatment of COPD.
出处
《中国医学创新》
CAS
2015年第3期4-6,共3页
Medical Innovation of China
基金
湖南省卫生厅科研基金课题(B2007-174)
长沙市科学技术协会课题(cx-2010-016)
关键词
慢性阻塞性肺疾病
急性加重期
肺气肿
临床特征
Chronic obstructive pulmonary disease
Acute exacerbation
Emphysema
Clinical characteristics
作者简介
通信作者：刘伟
