摘要
目的 探讨脑梗死患者与非脑梗死患者冠脉斑块类型及冠脉狭窄程度的差异.方法 选取2013年3～7月我院心内科收治的172例可疑冠心病患者,根据有无脑梗死病史,分为脑梗死组（46例）和非脑梗死组（126例）.所有患者均行冠脉双源CT,并对冠脉血管斑块节段（混合斑块节段、钙化斑块节段和非钙化斑块节段）计数.对两组患者冠脉斑块的类型及冠脉狭窄程度分析比较.结果 脑梗死组冠脉病变支数明显多于非脑梗死组（P=0.019）;脑梗死组冠脉斑块节段总数和混合斑块节段数明显多于非脑梗死组（P＜0.01）;脑梗死组与非脑梗死组相比,LM P=0.016,LAD P＜0.01,LCX P=0.003,RCA P=0.037,且混合斑块节段数明显多于非脑梗死组.结论 ①与无脑梗死病史的患者相比,有脑梗病史且合并疑似冠心病的患者,冠脉受累节段数明显较多;②冠脉混合斑块有可能是脑梗死的一个重要危险因素,但尚需进一步大样本研究.
Objective To investigate the relationship between cerebral infarction and the types of coronary plaques and the extent of coronary stenosis. Methods 172 patients with suspected coronary artery disease who were dived into cerebral infarction group （n=46） and control group without cerebral infarction （n= 126） received coronary dual-source computer angiograpby, then the number of three types of plaque segments were counted. The relationship between cerebral infarction and the types of coronary plaques and the extent of coronary stenosis was analyzed by SPSS software. Results More coronary arteries were involved in cerebral infarction group than in control group （P=0.019）. The number of total plaque segments and the number of total mixed plaque segments in cerebral infarction group were significantly more than those in control group （both P〈0.01 ）. The number of mixed plaque segments in LM（P=0.016）, LAD（P〈0.01）, LCX（P=0.003） and RCA（P=0.037） in cerebral infarction group were significantly more than that in control group. Conclusion （1）Compared to the control group, the cerebral infarction patients with suspected coronary disease may have more diseased coronary segments with mainly mixed plaques. （2）Mixed plaque of coronary artery may be a predictor of cerebral infarction. More research may be needed.
出处
《中国心血管病研究》
CAS
2015年第1期56-59,共4页
Chinese Journal of Cardiovascular Research
关键词
脑梗死
冠状动脉疾病
Cerebral infarction
Coronary artery disease
作者简介
通讯作者：王志广，E-mail：charlis789@126．com
