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奥曲肽辅助治疗急性上消化道出血的可行性研究 被引量:5

Feasibility Study of Octreotide in the Adjuvant Therapy of Acute Upper Gastrointestinal Hemorrhage
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摘要 目的:分析研究奥曲肽辅助兰索拉唑治疗急性上消化道出血的可行性。方法:将笔者所在医院收治住院的60例急性上消化道出血患者随机分为观察组(n=32)和对照组(n=28),观察组患者在确诊上消化道出血后用奥曲肽联合兰索拉唑治疗,对照组则在确诊后仅使用兰索拉唑治疗,比较分析两组患者止血率、平均止血时间。结果:观察组总有效30例(93.8%),对照组总有效20例(71.4%),观察组无效率(48 h内出血为停止)为6.3%,对照组为28.6%,两组药物止血效果比较差异有统计学意义(P<0.05)。结论:奥曲肽辅助兰索拉唑治疗上急性消化道出血较单独使用兰索拉唑效果好,具有较好的可行性。 Objective:To analyze the feasibility study of acute upper gastrointestinal hemorrhage with Octreotide and Lansoprazole.Method:Selected 60 acute upper gastrointestinal hemorrhage patients as the research treated in our hospital.They were randomly divided into the observation group(n=32) and the control group(n=28).The observation group treated with Octreotide and Lansoprazole after being diagnosed with acute upper gastrointestinal hemorrhage.And the control group treated with Lansoprazole.The rate of stopping bleeding and the average time of two groups were compared.Result:The total effective rate of the observation group was 93.8%,and the control group was 71.4%.The inefficiency rate of the observation group was 6.3%(stopping bleeding in 48 hours),the control group was 28.6%. The observation group was better than the control group in hemostatic effect,there was statistical significance(P〈0.05).Conclusion:Acute upper gastrointestinal hemorrhage treated with Octreotide and Lansoprazole is more effective than only using Octreotide,which has a good feasibility.
作者 邓准洲
机构地区 怀集县人民医院
出处 《中外医学研究》 2015年第1期12-13,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 奥曲肽 上消化道出血 兰索拉唑 止血效果 Octreotide Upper gastrointestinal hemorrhage Lansoprazole Hemostatic effect
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