摘要
目的探讨阿托伐他汀联合曲美他嗪治疗冠心病心绞痛的临床疗效。方法选取我院2012年5月—2014年3月收治的冠心病心绞痛患者48例,随机分为对照组和观察组,每组24例。对照组患者在常规治疗基础上给予曲美他嗪,观察组患者在对照组治疗基础上给予阿托伐他汀。观察两组患者心绞痛症状改善情况、心电图改善情况及治疗期间不良反应情况。结果观察组患者心绞痛症状改善总有效率为95.8%,高于对照组的66.7%(χ2=4.923,P<0.05)。观察组患者心电图改善总有效率为87.5%,高于对照组的62.5%(χ2=4.000,P<0.05)。两组患者治疗期间均未出现明显不良反应。结论阿托伐他汀联合曲美他嗪治疗冠心病心绞痛安全有效,有助于改善患者临床症状和心功能。
Objective To investigate the effect of atorvastatin combined with trimetazidine on coronary heart disease and angina pectoris.Methods From May 2012 to March 2014, 48 patients with coronary heart disease and angina pectoris in our hospital were selected and randomly divided into control group and observation group , each of 24 cases.Control group given trimetazidine based on conventional treatment , while observation group given atorvastatin based on the treatment of control group.Improvement of angina pectoris symptoms and ECG , and incidence of adverse reactions during treatment were observed . Results The total effective rate of improvement of angina pectoris symptoms of observation group was 95.8%, was higher than that of control group of 66.7% （χ^2 =4.923, P〈0.05）.The total effective rate of improvement of ECG of observation group was 87.5%, was higher than that of control group of 62.5% （χ^2 =4.000, P〈0.05） .No one of the two groups occurred ad-verse reactions during treatment .Conclusion Atorvastatin combined with trimetazidine is effective and safe on coronary heart disease and angina pectoris , which can improve the patients′angina pectoris symptoms and heart function .
出处
《实用心脑肺血管病杂志》
2014年第11期46-47,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
冠心病
心绞痛
阿托伐他汀
曲美他嗪
治疗结果
Coronary disease
Angina pectoris
Atorvastatin
Trimetazidine
Treatment outcome
