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免疫比浊法用于检测D-二聚体结果的相关分析

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摘要 目的对免疫比浊法在检测D-二聚体(D-D)结果的影响进行有效分析.方法: 随机收取我院2012 年3 月-2013 年10 月在我院进行健康体检与住院患者的标本共200 份,分别采用免疫比浊法与胶体金法对标本实施D-二聚体的进行重复性、稳定性与比对试验.结果:免疫比浊法在检测D-二聚体的重复性和稳定性明显优于胶体金法;而在比对试验中,免疫比浊法和胶体金法的比对结果回归方程为:y=0.3085x+748.06,而相关系数r 为0.938,说明两种方法的相关性并不是很理想;同时在DIC 诊断效能中两者方法的敏感度与特异度相差不大.结论:两种检测方法相比较,各自都有优势,在临床实验室检测中需根据具体情况来合理选择. Objective:to immune turbidimetric method in detection of D - dimer (D - D), the effects of the effective analysis. Methods:random charge from March 2012 toOctober 2013 in our hospital for physical examination and hospitalized patients, a total of 200 samples, immune turbidimetric method and colloidal gold method were used respectivelyto implement D - dimer for specimens for repeatability, stability and comparative test. Results:the immune turbidimetric method in detection of D - dimer of colloidal gold method isobviously better than the repeatability and stability; In comparison test, immune turbidimetric method and colloidal gold method comparing the results of regression equation is: y =0.3085 + 748.06 x, and the correlation coefficient r of 0.938, shows that the correlation of two methods is not very ideal; At the same time both the sensitivity of the method in the DICdiagnostic performance and specific degrees. Conclusion:compared two kinds of detection methods, each have advantages, in the clinical laboratory tests should be reasonable choiceaccording to specific situation.
作者 陆银宝
出处 《河南中医》 2014年第B11期349-349,共1页 Henan Traditional Chinese Medicine
关键词 免疫比浊法 D-二聚体 方法学评价 稳定性 比对实验 immunoturbidimetry D- two dimer method evaluation Stability comparison experiment
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