摘要
目的探讨甲氨蝶呤配伍米非司酮治疗剖宫产术后子宫瘢痕妊娠的临床效果。方法选取2008年8月～2014年8月本院收治的剖宫产术后子宫瘢痕妊娠患者80例,将其随机分为观察组和对照组,各40例,对照组采用甲氨蝶呤治疗,观察组在对照组的基础上配伍米非司酮治疗,两组均治疗6 d,比较两组的临床疗效,记录血β-HCG降至正常时间、包块大小及住院时间。结果观察组总有效率为87.5%,高于对照组的70.0%,差异有统计学意义（P〈0.05）。观察组血β-HCG降至正常时间及住院时间短于对照组,包块大小小于对照组,差异有统计学意义（P〈0.05）。结论甲氨蝶呤配伍米非司酮治疗剖宫产术后子宫瘢痕妊娠效果显著,可加快血β-HCG降至正常时间,缩短住院时间。
Objective To investigate the clinical effects of methotrexate combined with mifepristone in the treatment of cesarean scar pregnancy. Methods 80 patients with cesarean scar pregnancy admitted to our hospital from August 2008 to August 2014 were selected and randomly divided into observation group and control group,40 cases in each group,methotrexate was taken to the control group,mifepristone was added to the observation group based on control group treatment,both groups were treated for six days.The clinical efficacy of the two groups was compared,serum β-HCG decreased to normal time,mass size and length of stay in two groups were recorded. Results The total effective rate of observation group was 87.5%,higher than that of control group（70.0%）,with statistical difference（P〈0.05）.The serum β-HCG decreased to normal time and length of stay in observation group was shorter than that in control group respectively,the mass size in observation group was less than that in control group,with statistical difference（P〈0.05）. Conclusion Methotrexate combined with mifepristone in the treatment of cesarean scar pregnancy has significant effect,can accelerate blood β-HCG to normal time,shorten hospitalization time.
出处
《中国当代医药》
2014年第35期84-86,共3页
China Modern Medicine
关键词
甲氨蝶呤
米非司酮
剖宫产
瘢痕妊娠
Methotrexate
Mifepristone
Cesarean section
Scar pregnancy
