摘要
目的探讨小柴胡颗粒治疗经行发热的临床疗效。方法将128例患者随机分为两组,各64例。对照组采用酚麻美敏片(泰诺)治疗,观察组采用小柴胡颗粒治疗。治疗结束后随访3个月,观察两组患者临床疗效及经期体温变化。结果治疗的前2个周期,对照组患者经期体温在较观察组患者体温下降明显(P<0.05),治疗第3个周期时两组患者经期体温无明显差异(P>0.05)。随访第1个月时,两组患者经期平均体温无明显差异(P>0.05),从第2个月起,观察组患者经期平均体温明显低于对照组(P<0.05)。随访第1个月时,两组患者治愈率及总有效率无明显差异(P>0.05);第2个月时,观察组患者总有效率明显高于对照组(P<0.05),但治愈率无明显差异(P>0.05);第3个月时,观察组治愈率及总有效率均明显高于对照组(P<0.05)。用药过程中观察组患者不良反应总发生率明显低于对照组(P<0.05)。结论小柴胡颗粒治疗经行发热疗效确切、稳定,使用过程安全,是临床有效的治疗方法。
Objective To investigate the clinical effect of Xiaochaihu Granules in treating menstrual fever. Methods 128 patients with menstrual fever were randomly divided into 2 groups, 64 cases in each group. The control group was treated by Compound Pseu- doephedrine Hydroehloride Tablets（Tylenol） and the observation group was treated by Xiaoehaihu Granules. The 3- month follow up af- ter treatment was performed in the two groups. The clinical effects and the body temperature change during menstrual period were ob- served in the two groups. Results The body temperature during menstrual period in the first 2 cycles of treatment in the control group was significantly decreased compared with the observation group（P 〈 0.05）,but the body temperature during the third cycle of treat- ment had no statistically significant difference between the two groups（P 〉 0. 05）. During the first month of follow up,the mean body temperature had no statistically significant difference between the two groups（P 〉 0. 05）. The mean body temperature during menstrual period in the observation group began from the second month to be significantly lower than that in the control group（（P 〈 0.05）. The cure rate and the total effective rate during the first month of follow up had no statistical difference between the two groups, but the total effective rate at the second month of follow up in the observation group was significantly higher than that in the control group （P 〈 0.05）,but the cure rate had no significant difference between the two groups（P 〉 0.05）;the cure rate and the total effective rate at the third month of follow up in the observation group were significantly higher than those in the control group（ P 〈 0.05）. The total occurrence rate of adverse reactions during treatment process in the observation group was significantly lower than that in the con- trol group（ P 〈 0.05）. Conclusion Xiaochaihu Granules has definite and stable effect in treating menstrual fever, the use process is safe,which is an effective treatment method.
出处
《中国药业》
CAS
2014年第22期98-100,共3页
China Pharmaceuticals
关键词
经行发热
小柴胡颗粒
临床疗效
menstrual fever
Xiaochaihu Granules
clinical efficacy
作者简介
陈非（1983-），男，江苏连云港人，大学本科，主治医师，主要从事心内科临床工作，（电子信箱）Chenfeic@sina．com：
潘涛（1964-），女，山东人，博士研究生，教授，硕士研究生导师，主任医师，研究方向为西医内科学教学与研究，本文通讯作者，（电子信箱）funmoon6264@163．com。
