摘要
目的:评价临床药师对子宫肌瘤切除术患者围手术期抗菌药物应用进行干预的效果。方法:分别抽取该院2012年7–12月(干预前)和2013年1–6月(干预后)子宫肌瘤切除术出院患者病历共100份,对围手术期预防性应用抗菌药物的合理性进行比较。结果:干预后子宫肌瘤切除术围手术期患者预防性用药在药物选择、用药疗程、药物经济学方面较干预前有明显改善。干预前与干预后使用头孢菌素的比例分别为42.0%和72.0%;抗菌药物用药疗程合理率由12.0%升至60.0%,药物经济学合理率由50.0%升至86.0%,差异具有统计学意义(P<0.05);总药品费用占住院总费用的比例由51.0%降至49.3%,抗菌药物总费用占总药品费用的比例由30.2%降至28.8%;患者人均住院天数下降1.26 d。结论:临床药师对围术期预防应用抗菌药物进行干预的方法是可行且有效的,能提高医院抗菌药物的合理使用水平,减少患者的住院时间和住院费用,对临床安全、有效、经济的应用抗菌药物起到了积极作用。
Objective： To estimate the intervention effects by clinical pharmacist on the use of antibacterials during perioperative period of myomectomy. Methods： The clinical data were collected from 50 patients with myomectomy from July to December in 2012（before intervention） and 50 patients from January to June in 2013（after intervention）. The rationality of antibacterials application was evaluated thereafter. Results： After intervention by clinical pharmacists, the perioperative prophylactic application of antibacterials for myomectomy significantly improved in respect of antibacterials selection, medication duration and pharmacoeconomics. Before and after intervention, the percentages of cephalosporins use were 42.0% and 72.0%, respectively. The reasonable rate of medication duration of antibacterials rose from 12.0% to 60.0%, the reasonable rate of pharmacoeconomics rose from 50.0% to 86.0%, with statistical significance（P〈0.05）. The proportion of the total drug cost accounting for the total cost of hospitalization decreased from 51.0% to 49.3%, and the percentage of total antibacterials expense in the total medicine expense decreased from 30.2% to 28.8%. The mean hospitalization stay per patient decreased 1.26 days. Conclusion： The clinical pharmacists＇ intervention on the prophylactic application of antibacterials was feasible and effective, which can improve the rational application of antibacterials, decrease hospitalization stay and expense. It will promote safe, effective and economical use of antibacterials.
出处
《中国药物应用与监测》
CAS
2014年第5期315-318,共4页
Chinese Journal of Drug Application and Monitoring
基金
陕西省科技厅社会发展公关项目(013SF5-15)
作者简介
田云，女，主管药师，主要从事lI缶床药学与药事管理工作。E—mail：ty_524@hotmail．com
[通信作者]曹舫，女，主任药师，主要从事药理学与临床药学工作。E—mail：1398639949@qq.com
