摘要
多肽作为抗肿瘤药物的纳米载体，能够对药物进行修饰、包裹，在实现靶向性给药、缓释药物、提高药物水溶性及生物利用度、降低药物的毒副作用等方面表现出良好的应用前景，因而也成为近年来药剂学领域的研究热点之一。本文综述了近年来出现的纳米药物载体的种类，并详细阐述了各类载体的特点和优点，为其进一步应用提供理论依据。
As a carrier of anti -cancer drugs ,peptides can modify and coat drugs .It shows good pros-pects in targeted drug delivery ,drug sustained -releasing,drug enhancement of solubility ,bioavailability.It can also reduce side effects of drug .The related studies become one of the hot points in the field of pharmaceutical re-search in recent years .In this paper , the types of peptide based drug delivery emerged in recent years are re-viewed,the characteristics and advantages of various kinds of carrier systems are described in details .The present review provides a theoretical basis for the further application of peptide drug carries .
出处
《实用肿瘤学杂志》
CAS
2014年第5期465-468,共4页
Practical Oncology Journal
关键词
多肽
药物载体
抗肿瘤药物
Peptides
Drug carrier
Anti-cancer drugs
作者简介
马维娜，女，（1983-），硕士研究生，从事肿瘤药理学的研究。
通讯作者：孟拥军，E-mail：myjun5520@163．com
