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低白蛋白血症对脓毒症患者急性呼吸窘迫综合征发生和预后的预测作用 被引量：7

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摘要 目的:评价低白蛋白血症对脓毒症患者急性呼吸窘迫综合征(ARDS)发生和预后的预测作用。方法:以302例入住重症监护病房(ICU)并明确诊断脓毒症的患者为观察对象,按血清白蛋白(ALB)水平分为极低蛋白组、低蛋白组和正常蛋白组。收集全部患者诊断脓毒症即刻的血清白蛋白值、一般临床特征、ARDS发病率及28 d预后等相关资料,比较其差异性,用受试者工作曲线(ROC曲线)评价血清白蛋白水平与脓毒症合并ARDS患者预后的关系。结果:极低蛋白组与低蛋白组患者APACHEⅡ评分、血乳酸水平、ARDS发病率均明显高于正常蛋白组(P<0.05),3组间28 d病死率比较,差异无统计学意义;合并ARDS的患者中,极低蛋白组与低蛋白组28d病死率明显高于正常蛋白组(P<0.05);以血清白蛋白水平<25 g/L作为ARDS患者死亡预测的界点,敏感性为63%,特异性为86%。结论:低白蛋白血症与脓毒症患者ARDS的发生有关,并可以预测脓毒症合并ARDS患者的预后。
作者 刘壮 段美丽
机构地区 首都医科大学附属北京友谊医院重症医学科
出处 《实用医学杂志》 CAS 北大核心 2014年第20期3293-3295,共3页 The Journal of Practical Medicine
关键词 低白蛋白血症 脓毒症 急性呼吸窘迫综合征 预后
分类号 R459.7 [医药卫生—急诊医学]
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参考文献11

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同被引文献71

  • 1杨韶华,周佾龙,仝旭亚.动脉血乳酸和早期乳酸清除率对老年脓毒症患者预后判断的价值[J].中国老年学杂志,2014,34(7):1813-1814. 被引量：14
  • 2急性肺损伤／急性呼吸窘迫综合征诊断和治疗指南（2006）[J].中华急诊医学杂志,2007,16(4):343-349. 被引量：318
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实用医学杂志
2014年 第20期

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