摘要
目的:了解伴慢性肾功能不全的糖尿病患者发生糖尿病酮症的危险因素分析,为制定糖尿病干预方案提供科学依据。方法:选取我院既往诊断慢性肾功能不全,且符合糖尿病诊断标准的患者82例,采用问卷调查方式收集数据,分析发生糖尿病酮症的影响因素。结果:经单因素分析,有15项影响因素是糖尿病伴有肾功能不全患者发生糖尿病酮症的危险因素(P<0.05),经多因素Logistic回归分析显示伴有慢性肾功能不全的糖尿病患者发生糖尿病酮症的保护因素:年龄、并发症、用药依从性;而危险因素为HbA1c。结论:年龄越大、并发症越多、用药依从性好的患者,糖尿病酮症发病率有下降趋势;而HbA1c越高患者越容易发生糖尿病酮症。作为临床药师应定期集中患者进行教育,加强出院后随访,并个体化给药,从而确保血糖的有效控制,减少糖尿病酮症的发生。
Objective： To analyze the risk factors in the incidence of diabetic ketosis （DK） in diabetic patients complicated with chronic renal insufficiency （CRF）. Methods： Totally 82 diabetic patients with CRF were selected from our hospital. The data was collected using the questionnaire survey, and the influencing factors in the incidence of DK were analyzed. Results ： According to the single factor analysis, 15 influencing factors had statistical significance in the DK incidence. The Logistic regression analysis indicated that the incidence of DK in diabetic patients with CRF was negatively correlated with age, complication and medication compliance, while was positively correlated with HbAlc. Conclusion： The incidence of DK is decreased with the increase of age, complication and medication compliance, while the higher HbA1 c, the more DK occurs. Clinical pharmacists should pay attention to the regular patient education, strengthening the follow-up after discharge and individualized drug delivery in order to ensure the effective control of blood sugar and reduce the occurrence of DK.
出处
《中国药师》
CAS
2014年第9期1538-1541,共4页
China Pharmacist
关键词
慢性肾功能不全
糖尿病酮症
多因素分析
临床药师
Chronic renal insufficiency
Diabetic ketosis
Multiple factor analysis
Clinical pharmacist
作者简介
通讯作者：计成Tel：（025）83304616-66670E—mail：getcct@sina．com.
